Evidence map›Paper›PMID 33425686›Full record

ArticleToxicology reports2021

Toxicity of Dithiothreitol (DTT) to

Yiwen Wang, Maïlys Misto, Jing Yang, Nicole Gehring, Xiaoyu Yu, Bernard Moussian

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pathogenicity ofPathogens (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yiwen WangSchool of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China.
Maïlys MistoInterfaculty Institute for Cell Biology (Ifiz), University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.
Jing YangInterfaculty Institute for Cell Biology (Ifiz), University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.
Nicole GehringInterfaculty Institute for Cell Biology (Ifiz), University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.
Xiaoyu YuSchool of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China.
Bernard MoussianInterfaculty Institute for Cell Biology (Ifiz), University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.
University of Tübingen · DEInstitut de Biologie Valrose · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thiol-containing compound Dithiothreitol (DTT) has been shown to be toxic to cultured cells by inducing the generation of reactive oxygen species that ultimately cause cell death. However, its effects on multicellular organisms and the environment have not been investigated yet in detail. In this work, we tested the toxicity of DTT to the model insect

Indexed as

ApoptosisBarrierCncc/Keap1CuticleDrosophilaInsecticideOxidative stress

Identifiers

PMID33425686
PMCPMC7782319
OpenAlexW3114074143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.