Evidence map›Paper›PMID 33425344›Full record

ArticleAnnals of medicine and surgery (2012)2020

Combination of platelet-rich plasma and stromal vascular fraction on the level of transforming growth factor-β in rat subjects experiencing deep dermal burn injury.

Sachraswaty Rachman Laidding, Fonny Josh, Francisca, Muhammad Faruk, Andi Sinapati Palissei, Bayu Satria, Warsinggih, Agussalim Bukhari, Muh Nassrum Massi, Andi Asadul Islam

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sachraswaty Rachman LaiddingDivision of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Fonny JoshDivision of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
FranciscaDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Muhammad FarukDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Andi Sinapati PalisseiDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Bayu SatriaDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
WarsinggihDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Agussalim BukhariDepartment of Clinical Nutrition, Faculty of Medicine, Hasanuddin University, Sulawesi Selatan, Indonesia.
Muh Nassrum MassiDepartment of Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Andi Asadul IslamDepartment of Neurosurgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Hasanuddin University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe combination of stromal vascular fraction (SVF) and platelet-rich plasma (PRP) is effective at increasing the concentration of growth factors including transforming growth factor-β (TGF-β). The increase in this growth factor is expected to accelerate the healing of burns. This study aims to determine the effect of giving a combination of SVFs and PRP on TGF-β levels in the healing process of deep dermal burns.

methodsThis was an experimental study in 64 rats using a post-test control group design consisting of 1 group of SVFs and PRP combination injection treatment group, 1 group given a topical combination of SVFs and PRP, 1 group given Vaseline, and 1 control group.

resultsThere was a significant difference in TGF-β levels between the deep dermal burns group that was given a combination of SVFs and PRP injection and topical, the Vaseline group, and the control group with p-value <0.05.

conclusionThe combination of SVFs and PRP increases the level of TGF-β in the healing process of deep dermal burns.

Indexed as

Burn injuryExperimental researchPlatelet-rich plasmaStromal vascular fractionTGF-β

Identifiers

PMID33425344
PMCPMC7779951
OpenAlexW3111813126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.