Evidence map›Paper›PMID 33425246›Full record

ReviewComputational and structural biotechnology journal2021

Exploring the impact of intestinal ion transport on the gut microbiota.

Amy C Engevik, Melinda A Engevik

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Review
  9. Marine drugs · 2025
    Article
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  11. Article
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  14. Review
  15. Article
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  19. Milk andAmerican journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Amy C EngevikDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Melinda A EngevikDepartment of Regenerative Medicine & Cell Biology, Medical University of South Carolina, SC 29455, USA.
Medical University of South Carolina · USVanderbilt University Medical Center · US

Funding

Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8M
NIDDK NIH HHS P30 DK123704
6 · The paper itself

Abstract

The gut microbiota and the host are intimately connected. The host physiology dictates the intestinal environment through regulation of pH, ion concentration, mucus production,

Indexed as

CFTRCFTR, cystic fibrosis transmembrane regulatorClC, chloride channelDRADRA, down-regulated in adenomaENaC, epithelial Na+ channelGastrointestinalGI, gastrointestinalGLUT2GLUT2, glucose transporter 2Ion transportMicrobiomeMicrobiotaNHE2NHE2, sodium-hydrogen exchanger isoform 2NHE3NHE3, sodium-hydrogen exchanger isoform 3NKCC1, Na+-K+-2Cl− co-transporterOTUs, operational taxonomic unitsSGLT1, sodium glucose co-transporter 1

Identifiers

PMID33425246
PMCPMC7773683
OpenAlexW3111058140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.