Evidence map›Paper›PMID 33425190›Full record

ArticleThe Pan African medical journal2020

[Determinants of non-compliance with antiretroviral therapy in adult patients in Kinshasa].

Benilde Bepouka Izizag, Hippolyte Situakibanza, Florian Kiazayawoko, Aliocha Nkodila, Eric Mafuta, Philippe Lukanu, Henry Mukumbi, Murielle Longokolo, Madone Mandina, Nadine Mayasi and 4 more

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Benilde Bepouka IzizagService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Hippolyte SituakibanzaService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Florian KiazayawokoService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Aliocha NkodilaCités des Aveugles, Kinshasa, République Démocratique du Congo.
Eric MafutaEcole de Santé Publique, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Philippe LukanuDépartement de Médecine de Famille, Université Protestante au Congo, Kinshasa, République Démocratique du Congo.
Henry MukumbiACS AMO-CONGO (ONG-ASBL/Santé), Kinshasa, République Démocratique du Congo.
Murielle LongokoloService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Madone MandinaService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Nadine MayasiService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
Amede KinukaCliniques Rapha, Kinshasa, République Démocratique du Congo.
Evelyne AmaelaCliniques Rapha, Kinshasa, République Démocratique du Congo.
Willy KazadiCliniques Rapha, Kinshasa, République Démocratique du Congo.
Marcel MbulaService des Maladies Infectieuses et Tropicales, Département de Médecine Interne, Cliniques Universitaires, Faculté de Médecine, Université de Kinshasa, Kinshasa, République Démocratique du Congo.
University of Kinshasa · CDHospital for Tropical Diseases · VNProgramme National Multisectoriel de Lutte contre le sida · CDUniversité Protestante au Congo · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionthe purpose of this study was to identify the determinants of non-compliance of persons living with HIV with antiretroviral treatment in Kinshasa.

methodswe conducted a cross-sectional study in Kinshasa from 1

resultsthe 400 patients living with HIV had a median age of 43 years (18-75). Global non-compliance rate was 25.5%. Objective non-compliance rate was higher than that of subjective non-compliance (29% vs 21%, p = 0.01). Payment for consultation [adjusted odds ratio (AOR): 1.70; 95% confidence interval (95% CI): 1.02-2.81; p = 0.042), adverse reactions (AOR: 2.23; 95% CI: 1.33-3.75; p = 0.002) and the lack of awareness that missing a dose may worsen disease (AOR: 4.16; 95% CI: 1.04-16.68; p = 0.045) were determinants of non-compliance. Having trusted person was a protective factor versus non-compliance (AOR: 0.54; 95% CI: 0.39-0.93; p = 0.004).

conclusionthe rate of non-compliance with antiretroviral treatment is high in Kinshasa. The evaluation of determinants is necessary to establish strategies for improving compliance.

Indexed as

Drug MonitoringAdolescentAdultAgedAnti-HIV AgentsCross-Sectional StudiesDemocratic Republic of the CongoFemaleHIV InfectionsHumansMaleMiddle AgedProtective FactorsRisk FactorsYoung AdultAnti-HIV AgentsAntiretroviral therapydeterminantsKinshasanon-compliance

Identifiers

PMID33425190
PMCPMC7757311
OpenAlexW3120362871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.