Evidence map›Paper›PMID 33425177›Full record

Observational studyThe Pan African medical journal2020

Predictors of AIDS-related death among adult HIV-infected inpatients in Kisangani, the Democratic Republic of Congo.

Alliance Tagoto Tepungipame, Serge Tonen-Wolyec, Ginette Claude Kalla, Eugeune Basandja Longembe, Rachel Olonga Atike, Joris Losimba Likwela, Francois-Xavier Mbopi-Kéou, Laurent Bélec, Salomon Batina-Agasa

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Public health action · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alliance Tagoto TepungipameFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Serge Tonen-WolyecFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Ginette Claude KallaFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Eugeune Basandja LongembeFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Rachel Olonga AtikeFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Joris Losimba LikwelaFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Francois-Xavier Mbopi-KéouFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Laurent BélecLaboratory of Virology, Hôpital Européen Georges Pompidou, and University of Paris Descartes, Paris Sorbonne Cité, Paris, France.
Salomon Batina-AgasaFaculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Université de Kisangani · CDUniversité de Yaoundé I · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHuman Immunodeficiency Virus (HIV) infection continues to be a major public health concern in sub-Saharan Africa. We aimed to evaluate potential factors associated with AIDS-related death among adult HIV-infected inpatients in Kisangani, the Democratic Republic of the Congo (DRC).

methodsthis is a hospital-based retrospective, observational analysis carried out between 1

resultsa total of 347 HIV-infected inpatients were included. Among those, the rate of AIDS-related death was 25.1% (95% CI: 20.8-29.9). The rates of AIDS-related death were lower among patients with a university education (aOR: 0.03 [95% CI: 0.00-1.0]) and higher among patients in WHO clinical stage 4 (aOR: 15.4 [6.8-27.8]), patients with poor highly active antiretroviral therapy (HAART) observance (aOR: 14.5 [2.3-40.4), and patients suffering from opportunistic infections (aOR: 9.3 [95% CI: 3.4-25.1]), including cryptococcal meningitis (aOR: 27 [95% CI: 6.0-125.7]) and viral infections associated with zona and Kaposi sarcoma (aOR: 4.8 [95% CI: 2.2-10.4]).

conclusionin our retrospective study on a large sample of inpatients hospitalized in Kisangani, classic causes of death were found. The association with the low level of education suggests that the economic level of the patients who die is a determining factor, difficult to correct. The identification of a limited number of other factors will allow a better medical management.

Indexed as

Acquired Immunodeficiency SyndromeAdolescentAdultAIDS-Related Opportunistic InfectionsAntiretroviral Therapy, Highly ActiveDemocratic Republic of the CongoEconomic FactorsFemaleHIV InfectionsHospitalizationHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSocioeconomic FactorsAIDS-related deathDemocratic Republic of the CongoHIVHIV-infected inpatientspredictors

Identifiers

PMID33425177
PMCPMC7757268
OpenAlexW3092393834

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.