Evidence map›Paper›PMID 33425160›Full record

ArticleThe Pan African medical journal2020

[Administration of analgesics at home for the treatment of vaso-occlusive crises before admission to hospital].

Alima Yanda Anastasie Nicole, Eposse Ekoube Charlotte, Ngatsing Christelle Shanti, Mandeng Ma Linwa Edgar, Françoise Ngnedjou Nwabufor Foute, Ngou Patrick, Mbono Ritha, Djike Puepi Yolande, Epee Patricia, Wete Estelle and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Alima Yanda Anastasie NicoleInstitut Supérieur de Technologie Médicale, Yaoundé, Cameroun.
Eposse Ekoube CharlotteCentre de Prise en Charge des Drépanocytaires, Hôpital Laquintinie, Douala, Cameroun.
Ngatsing Christelle ShantiCentre Mère et Enfant Fondation Chantal BIYA, Yaoundé, Cameroun.
Mandeng Ma Linwa EdgarFaculty of Health Sciences, University of Buea, Buea, Cameroun.
Françoise Ngnedjou Nwabufor FouteUniversité Adventiste Cosendai, Nanga Eboko, Cameroun.
Ngou PatrickFaculté de Médecine et des Sciences Biomédicales, Yaoundé, Cameroun.
Mbono RithaFaculté de Médecine et des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroun.
Djike Puepi YolandeFaculty of Health Sciences, University of Buea, Buea, Cameroun.
Epee PatriciaFaculté de Médecine et des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroun.
Wete EstelleCentre Mère et Enfant Fondation Chantal BIYA, Yaoundé, Cameroun.
Koki Ndombo Paul OlivierCentre Mère et Enfant Fondation Chantal BIYA, Yaoundé, Cameroun.
Centre International De Reference Chantal Biya · CMUniversity of Douala · CMUniversity of Buea · CMAdventist University Cosendai · CMInstitut Supérieur de Technologie Médicale · CMUniversité de Yaoundé I · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionvaso-occlusive crises (VOCs) are the primary reason for admission and hospitalization in children with sickle cell disease and most often they require home care before arriving to consultation. The purpose of this study was to describe home-based therapy for children with sickle cell disease admitted with VOCs.

methodswe conducted a descriptive and analytical cross-sectional study, in the pediatric emergencies at the Mother and Child Centre of the Chantal Biya Foundation (CBF) over a 4-month period from February to May 2018. Consecutive sampling was used. All patients with sickle cell disease presenting with VOCs were included in the study.

resultsone hundred and fifty-two patients were enrolled. The most represented age group was 5- 10 years. Eighty-two patients (54%) presented more than 24 hours after the onset of the crises and 70 (46%) in the first 24 hours; 80% (n=122) of our sample had received analgesic treatment at home. Escalation of therapy was found in 31.2% of cases. The use of prescription medications (75.4%, n=92) was dominant as the 1

conclusionthis study shows that home-based management of VOCs is inadequate. Measures must be taken to ensure that all patients with sickle cell disease can effectively manage minor to moderate VOCs at home.

Indexed as

AdolescentAnalgesicsAnemia, Sickle CellChildChild, PreschoolCross-Sectional StudiesDose-Response Relationship, DrugDrug OverdoseFemaleHospitalizationHumansInfantMalePrescription DrugsAnalgesicsPrescription DrugsanalgesicTreatmentvaso-occlusive crises

Identifiers

PMID33425160
PMCPMC7755375
OpenAlexW3092252736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.