Trial reportPain research & management2020
Open-Label Placebo Trial among Japanese Patients with Chronic Low Back Pain.
Trial report in Pain research & management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review and meta analysis of open label placebo effects in chronic musculoskeletal pain.Scientific reports · 2025Pooled it
- Open label placebo for chronic low back pain: a systematic review and meta-analysis of randomized controlled trials.Pain management · 2025Pooled it
- Impact of contextual factors on patient outcomes following conservative low back pain treatment: systematic review.Chiropractic & manual therapies · 2022Pooled it
- Placebo effects in low back pain: A systematic review and meta-analysis of the literature.European journal of pain (London, England) · 2021 · on this mapPooled it
- Open-label placebo treatment does not enhance cognitive abilities in healthy volunteers.Scientific reports · 2023Trial
- Effect of quick simple exercise on non-specific low back pain in Japanese workers: a randomized controlled trial.Environmental health and preventive medicine · 2023Trial
- The Possibility of Open-Label Use of Placebo in Healthcare Practice: A Systematic Review of Recent Clinical Trials.Cureus · 2025Review
- Article
- Boosting open-label placebo effects in acute induced pain in healthy adults (BOLPAP-study): study protocol of a randomized controlled trial.Frontiers in medicine · 2024Article
- Open-Label Placebo Effects on Psychological and Physical Well-Being: A Conceptual Replication Study.Clinical psychology in Europe · 2022Article
- Can the Open Label Placebo Rationale Be Optimized?Frontiers in pain research (Lausanne, Switzerland) · 2021Article
- Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial.Frontiers in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to confirm the effectiveness of open-label placebo (OLP) in Japanese patients with chronic low back pain (CLBP), similar to previous reports, and to investigate its short- and medium-term effects in this study population. Methods: Fifty-two patients with CLBP were randomized into a treatment as usual (TAU) group ( Results: Although all participants completed the 3-week follow-up, four patients (two in each group) were lost to follow-up beyond week 3. There were no significant intergroup differences in changes in the RMDQ score ( Conclusions: The OLP + TAU group showed no superior findings in comparison with the TAU group after 3 weeks and 12 weeks for Japanese patients with CLBP. Nonetheless, significant improvements in functional disability were observed in both groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.