Evidence map›Paper›PMID 33424988›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Percutaneous Needle Electrolysis Reverses Neurographic Signs of Nerve Entrapment by Induced Fibrosis in Mice.

R Margalef, F Valera-Garrido, F Minaya-Muñoz, M Bosque, N Ortiz, M M Santafe

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

R MargalefUnit of Histology and Neurobiology, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Rovira i Virgili University, Carrer St. Llorenc, No. 21, 43201 Reus, Spain.ORCID https://orcid.org/0000-0003-4109-7227
F Valera-GarridoMVClinic Institute, Madrid, Spain.ORCID https://orcid.org/0000-0002-8867-2519
F Minaya-MuñozMVClinic Institute, Madrid, Spain.ORCID https://orcid.org/0000-0002-6337-2501
M BosqueUnit of Histology and Neurobiology, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Rovira i Virgili University, Carrer St. Llorenc, No. 21, 43201 Reus, Spain.ORCID https://orcid.org/0000-0002-3350-8447
N OrtizNeurology Department, Hospital Universitari Sant Joan de Reus, 43202 Reus, Spain.
M M SantafeUnit of Histology and Neurobiology, Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Rovira i Virgili University, Carrer St. Llorenc, No. 21, 43201 Reus, Spain.ORCID https://orcid.org/0000-0002-5462-5108
Universitat Rovira i Virgili · ESUniversidad San Pablo CEU · ESHospital Universitari Sant Joan de Reus · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve entrapments such as carpal tunnel syndrome are the most common mononeuropathies. The lesional mechanism includes a scarring reaction that causes a vascular compromise. The most effective treatment is surgery, which consists of removing the scarred area, thus reverting the vascular impairment. In the present study, a more conservative therapeutic approach has been undertaken to release the nerve by means of galvanic current (GC) applied with a needle: percutaneous needle electrolysis (PNE). For this purpose, a mouse model of sciatic nerve entrapment has been created using albumin coagulated by glutaraldehyde (albumin 35% and glutaraldehyde 2% volume applied, 10

Identifiers

PMID33424988
PMCPMC7772050
OpenAlexW3115951571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.