Evidence map›Paper›PMID 33424846›Full record

ReviewFrontiers in immunology2020

Intestinal Microbes in Autoimmune and Inflammatory Disease.

Wan-Jung H Wu, Daniel F Zegarra-Ruiz, Gretchen E Diehl

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Observational
  2. Review
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  10. Review
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  12. Observational
  13. Article
  14. The Effects of Mammary GlandInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Review
  17. Article
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  19. Article
  20. Systemic Lupus Erythematosus Risk: The Role of Environmental Factors.Rheumatic diseases clinics of North America · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wan-Jung H WuImmunology Graduate Program, Baylor College of Medicine, Houston, TX, United States.
Daniel F Zegarra-RuizImmunology Program of the Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Gretchen E DiehlImmunology Program of the Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Orchestrating intestinal immunity through microbiota-CX3CR1+ cell interactions R01AI125264 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI GRETCHEN E DIEHL · 2017 to 2026
$4.1M
NCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI125264
6 · The paper itself

Abstract

Autoimmune diseases and chronic inflammatory disorders are characterized by dysregulated immune responses resulting in excessive and uncontrolled tissue inflammation. Multiple factors including genetic variation, environmental stimuli, and infection are all thought to contribute to continued inflammation and pathology. Current evidence supports the microbiota as one such factor with emerging data linking commensal organisms to the onset and progression of disease. In this review, we will discuss links between the microbiota and specific diseases as well as highlight common pathways that link intestinal microbes with multiple autoimmune and inflammatory diseases.

Indexed as

AutoimmunityDisease SusceptibilityGastrointestinal MicrobiomeAnimalsAutoantibodiesAutoimmune DiseasesDysbiosisHumansInflammationOrgan SpecificityAutoantibodiesautoimmunityinflammationinflammatory bowel diseaseintestinal microbiotamultiple sclerosisrheumathoid arthritissystemic lupus erythematosustype 1 diabetes

Identifiers

PMID33424846
PMCPMC7786055
OpenAlexW3116655839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.