Evidence map›Paper›PMID 33424828›Full record

ReviewFrontiers in immunology2020

Acquired Hemophilia A in IgG4-Related Disease: Case Report, Immunopathogenic Study, and Review of the Literature.

Sébastien Sanges, Emmanuelle Jeanpierre, Benjamin Lopez, Jules Russick, Sandrine Delignat, Benjamin Carpentier, Romain Dubois, Sylvain Dubucquoi, Thomas Guerrier, Éric Hachulla and 6 more

Open access · goldAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Sébastien SangesUniv. Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
Emmanuelle JeanpierreCHU Lille, Institut d'Hématologie Transfusion, Lille, France.
Benjamin LopezCHU Lille, Institut d'Immunologie, Lille, France.
Jules RussickCentre de recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France.
Sandrine DelignatCentre de recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France.
Benjamin CarpentierService d'Hématologie, Hôpital Saint-Vincent, GHICL, Lille, France.
Romain DuboisCHU Lille, Institut de Pathologie, Lille, France.
Sylvain DubucquoiUniv. Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
Thomas GuerrierUniv. Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
Éric HachullaUniv. Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
Pierre-Yves HatronCHU Lille, Département de Médecine Interne et Immunologie Clinique, Lille, France.
Camille ParisCHU Lille, Institut d'Hématologie Transfusion, Lille, France.
Sophie SusenCHU Lille, Institut d'Hématologie Transfusion, Lille, France.
David LaunayUniv. Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille, France.
Sébastien Lacroix-DesmazesCentre de recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France.
Louis TerriouCHU Lille, Département de Médecine Interne et Immunologie Clinique, Lille, France.
Centre Hospitalier Universitaire de Lille · FRInserm · FRHôpital Nord · FRUniversité de Lille · FRHôpital Saint-Vincent-de-Paul · FRInstitute for Translational Research in InflammationInstitut Pasteur de Lille · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the observation of a 75-year-old patient referred for cervical lymphadenopathies. A pre-lymphadenectomy blood work revealed an asymptomatic elevation of aPTT with low factor VIII (FVIII) levels and high anti-FVIII antibodies titers, consistent with acquired hemophilia A (AHA). Histological work-up of a cervical lymphadenopathy revealed benign follicular hyperplasia with IgG4

Indexed as

AgedAutoantibodiesBlood CoagulationBlood Coagulation TestsDisease SusceptibilityFactor VIIIFemaleHemophilia AHumansImmunoglobulin GImmunoglobulin G4-Related DiseaseImmunohistochemistryLymph NodesMaleT-Lymphocytes, RegulatoryAutoantibodiesF8 protein, humanFactor VIIIImmunoglobulin Gacquired hemophilia Aanti-factor VIII autoantibodiesIgG4 antibodiesIgG4-related diseaseplasma cell

Identifiers

PMID33424828
PMCPMC7793697
OpenAlexW3115526039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.