Evidence map›Paper›PMID 33424823›Full record

ArticleFrontiers in microbiology2020

The Antibiotic Andrimid Produced by

Yannick Buijs, Thomas Isbrandt, Sheng-Da Zhang, Thomas Ostenfeld Larsen, Lone Gram

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Co-existence of two antibiotic-producing marine bacteria:Applied and environmental microbiology · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yannick BuijsDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Thomas IsbrandtDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Sheng-Da ZhangDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Thomas Ostenfeld LarsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Lone GramDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Technical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development and spread of multidrug resistant pathogens have reinforced the urgency to find novel natural products with antibiotic activity. In bacteria, orphan biosynthetic gene clusters (BGCs) far outnumber the BGCs for which chemistry is known, possibly because they are transcriptionally silent under laboratory conditions. A strategy to trigger the production of this biosynthetic potential is to challenge the microorganism with low concentrations of antibiotics, and by using a

Indexed as

antibioticsbiosynthetic gene clusternatural product discoverystress responseVibrionaceae

Identifiers

PMID33424823
PMCPMC7793655
OpenAlexW3116037210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.