ArticleFrontiers in microbiology2020
Dietary Lipid:Protein Ratio and n-3 Long-Chain Polyunsaturated Fatty Acids Alters the Gut Microbiome of Atlantic Salmon Under Hypoxic and Normoxic Conditions.
Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Replacing fish oil with Tetraselmis chui microalgae biomass does not compromise rainbow trout health: Biochemical, histologic, antioxidant and immune gene expression.Scientific reports · 2026Article
- Tetrodotoxin (TTX) reshapes the functional potential of the gut microbiome in juvenile tiger pufferfish (Takifugu rubripes) across salinity gradients.Animal microbiome · 2026Article
- Oleanolic Acid Modulates the Gut-Liver Axis to Alleviate High-Fat Diet-Induced Hepatic Lipid Deposition in Nile Tilapia (Microorganisms · 2026Article
- Genotypic characterization of gut isolates from Atlantic salmon fry reveals beneficial microbes with biotechnological potential.Applied and environmental microbiology · 2026Article
- Fatty Acids as Prebiotics and Their Role in Antibiofilm Activity.Antibiotics (Basel, Switzerland) · 2026Review
- Article
- DHA-Rich Algae Feed Modulates Atlantic Salmon Health, Microbiota and Stress Response.Aquaculture nutrition · 2026Article
- Alterations and resilience of intestinal microbiota to increased water temperature are accompanied by the recovery of immune function in Nile tilapia.Scientific reports · 2025Article
- Dietary Nucleotides Improve Growth of JuvenileAquaculture nutrition · 2025Article
- Effects of Dietary Protein to Lipid Ratio and Insect Meal on Growth Performance, Feed Utilization, and the Gut Microbiome of Lake Whitefish (Aquaculture nutrition · 2025Article
- Characterization of bacteria colonizing the mucosal layer of the gastrointestinal tract of Atlantic salmon farmed in a warm water region.Frontiers in microbiology · 2025Article
- Understanding the role of microbes in health and disease of farmed aquatic organisms.Marine life science & technology · 2024Article
- Genomic and functional characterization of the Atlantic salmon gut microbiome in relation to nutrition and health.Nature microbiology · 2024Article
- Dietary Chlorella vulgaris supplementation modulates health, microbiota and the response to oxidative stress of Atlantic salmon.Scientific reports · 2024Article
- Fecal microbiota transplantation accelerates restoration of florfenicol-disturbed intestinal microbiota in a fish model.Communications biology · 2024Article
- The impact of tetrodotoxin (TTX) on the gut microbiome in juvenile tiger pufferfish, Takifugu rubripes.Scientific reports · 2024Article
- Effect of fatty acid-enriched black soldier fly larvae meal combined with chitinase on the metabolic processes of Nile tilapia.The British journal of nutrition · 2024Article
- Effects of plant-based proteins and handling stress on intestinal mucus microbiota in rainbow trout.Scientific reports · 2023Article
- Intestinal Microbiota Community and Blood Fatty Acid Profiles of Albas Cashmere Goats Fed with Flaxseed Oil and Whole Flaxseed.Animals : an open access journal from MDPI · 2023Article
- Exploring gut microbiota in adult Atlantic salmon (Salmo salar L.): Associations with gut health and dietary prebiotics.Animal microbiome · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Researchers have adjusted dietary lipid:protein ratios and n-3 long-chain polyunsaturated fatty acids (LC-PUFA) to optimize the growth performance of Atlantic salmon. However, dietary impacts on the gut microbiome are lacking, especially under varying environmental conditions. To examine this response, post-smolt salmon (184 ± 5 g) were fed diets with lipid:protein ratios considered low (180, 570 g/kg) and high (230, 460 g/kg) along with low and high levels of n-3 LC-PUFA (7 or 14 g/kg) while fish were reared under low and high levels of dissolved oxygen (6.7 or 8.0 mg/L). At day 0, 35 and 116, digesta in the distal intestine were collected and analyzed for viable counts and 16S ribosomal RNA (rRNA) genes (V4 region) using Illumina MiSeq. The reduction in oxygen had negligible effects, except on viable plate counts of total bacteria and an initial effect on beta-diversity. In contrast, the high lipid (HL) diets had an increased alpha-diversity (e.g., Shannon and Chao-1) at day 0 and day 35 whereas high n-3 diets suppressed these indices at day 116. Generally, a reduction in alpha-diversity was observed over time and an interaction between lipid:protein ratio x n-3 was found. Between diets, beta-diversity and phyla abundance were similar as both Proteobacteria (44%) and Firmicutes (21%) dominated. However, at the genus level
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