ArticleFrontiers in psychiatry2020
The Efficacy of Fecal Microbiota Transplantation for Children With Tourette Syndrome: A Preliminary Study.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation.Microbiome · 2025Pooled it
- Emerging therapeutic approaches for Tourette syndrome and other tic disorders - a systematic review of current clinical trials.European child & adolescent psychiatry · 2025Pooled it
- Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases.Nature medicine · 2022Pooled it
- Efficacy of the Jingxin Zhidong Formula for Tic Disorders: A Randomized, Double Blind, Double Dummy, Parallel Controlled Trial.Neuropsychiatric disease and treatment · 2022Trial
- Xifeng Zhichou decoction mitigates tic disorder on juvenile rats by regulating neuroinflammation and neurotransmitter homeostasis: dual modulation of Nr4a2 and gut microbiota.Chinese medicine · 2026Article
- Early Gut Microbiota and Neurodevelopmental Trajectories: Implications for Pediatric Neuropsychiatric Vulnerability-A Narrative Review.Nutrients · 2026Review
- Neurodevelopmental disorders and the gut microbiome: insights into ADHD and tic disorders.Frontiers in microbiology · 2026Review
- Gut: The gate and key to brain.Chinese medical journal · 2025Review
- Possible Applications of Fecal Microbiota Transplantation in the Pediatric Population: A Systematic Review.Biomedicines · 2025Review
- Effects and mechanisms of vitamins A and D on behavior associated with Tourette syndrome in rats.Frontiers in nutrition · 2025Article
- Probiotic potential ofFrontiers in microbiology · 2025Article
- Neurodevelopmental Disorders Associated with Gut Microbiome Dysbiosis in Children.Children (Basel, Switzerland) · 2024Review
- Article
- A preliminary study for the clinical effect of one combinational physiotherapy and its potential influence on gut microbial composition in children with Tourette syndrome.Frontiers in nutrition · 2023Article
- The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees.Frontiers in microbiology · 2023Article
- Drivers and determinants of strain dynamics following fecal microbiota transplantation.Nature medicine · 2022Article
- Tourette Syndrome Treatment Updates: a Review and Discussion of the Current and Upcoming Literature.Current neurology and neuroscience reports · 2022Review
- KOMB: K-core based de novo characterization of copy number variation in microbiomes.Computational and structural biotechnology journal · 2022Article
- Big data analytics frameworks for the influence of gut microbiota on the development of tic disorder.Frontiers in computational neuroscience · 2022Article
- Tourette syndrome research highlights from 2020.F1000Research · 2022Review
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Therapies for Tourette syndrome (TS) are insufficient, and novel therapies are needed. Fecal microbiota transplantation (FMT) has been a potential therapy for several neurological diseases. Here, we report a preliminary study to investigate the effects of FMT on patients with TS. Five patients with TS received a single administration of FMT via endoscopy. Tic symptoms were assessed by Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) and adverse effects were recorded at week 8 following FMT. Lipopolysaccharide (LPS) levels and 14 cytokines levels were measured. The microbiota profile in feces were analyzed by shotgun metagenomics. Four patients (4/5) responded positively to FMT (YGTSS-TTS reduction rate >25%) at week 8 with high safety. The levels of LPS and cytokines varied after FMT. FMT shifted the composition of the gut microbiota in patients close to that of the donor and continuously changed the abundance of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.