Evidence map›Paper›PMID 33424641›Full record

ArticleFrontiers in physiology2020

Mitochondrial Calcium Uniporter Deficiency in Zebrafish Causes Cardiomyopathy With Arrhythmia.

Adam D Langenbacher, Hirohito Shimizu, Welkin Hsu, Yali Zhao, Alexandria Borges, Carla Koehler, Jau-Nian Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Genome wide identification of theFrontiers in microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. CaCells · 2022
    Review
  15. Modeling Human Cardiac Arrhythmias: Insights from Zebrafish.Journal of cardiovascular development and disease · 2022
    Review
  16. Zebrafish Heart Failure Models.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adam D LangenbacherDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
Hirohito ShimizuDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
Welkin HsuDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
Yali ZhaoDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
Alexandria BorgesDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
Carla KoehlerDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, United States.
Jau-Nian ChenDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · US

Funding

Rtf1-dependent transcriptional regulation of heart developmentR01HL140472 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, JAU-NIAN, TRINH, LE A. · 2018 to 2021
$1.6M
Elucidating the molecular mechanisms regulating embryonic cardiac rhythmicityR01HL096980 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, JAU-NIAN · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL096980NHLBI NIH HHS R01 HL140472
6 · The paper itself

Abstract

Mitochondrial Ca

Indexed as

arrhythmiacardiomyopathymitochondriamitochondrial calcium uptakesinus arrest

Identifiers

PMID33424641
PMCPMC7785991
OpenAlexW3113829911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.