Evidence map›Paper›PMID 33424609›Full record

ArticleFrontiers in pharmacology2020

Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans.

Sarah C Simões, André L Balico-Silva, Lucas T Parreiras-E-Silva, André L B Bitencourt, Michel Bouvier, Claudio M Costa-Neto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Insights Into the Role of Angiotensin-II ATHypertension (Dallas, Tex. : 1979) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sarah C SimõesRibeirao Preto Medical School, Department of Biochemistry and Immunology, University of São Paulo, Ribeirao Preto, Brazil.
André L Balico-SilvaRibeirao Preto Medical School, Department of Biochemistry and Immunology, University of São Paulo, Ribeirao Preto, Brazil.
Lucas T Parreiras-E-SilvaRibeirao Preto Medical School, Department of Biochemistry and Immunology, University of São Paulo, Ribeirao Preto, Brazil.
André L B BitencourtRibeirao Preto Medical School, Department of Biochemistry and Immunology, University of São Paulo, Ribeirao Preto, Brazil.
Michel BouvierDepartment of Biochemistry and Molecular Medicine and Institute for Research in Immunology and Cancer, University of Montréal, Montréal, QC, Canada.
Claudio M Costa-NetoRibeirao Preto Medical School, Department of Biochemistry and Immunology, University of São Paulo, Ribeirao Preto, Brazil.
Universidade de São Paulo · BRUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AT1 receptor (AT1R) has a major role in the Renin-Angiotensin System, being involved in several physiological events including blood pressure control and electrolyte balance. The AT1R is a member of the G protein coupled receptors (GPCR) family, classically known to couple G

Indexed as

AngIIAngiotensin II receptorAT1 receptorcardiovascular diseasesmutationssignalling

Identifiers

PMID33424609
PMCPMC7786401
OpenAlexW3113873160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.