Evidence map›Paper›PMID 33424288›Full record

ReviewSaudi journal of biological sciences2021

Role of calcineurin biosignaling in cell secretion and the possible regulatory mechanisms.

Hani Alothaid, Mohammed S K Aldughaim, Saad Saeed Alamri, Jehan Saad M Alrahimi, Saeedah Hamdan Al-Jadani

Open access · hybridAbstract readReview
In one paragraph

Review in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Calcineurin inhibition may prevent Alzheimer disease in people with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hani AlothaidDepartment of Basic Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, Saudi Arabia.
Mohammed S K AldughaimResearch Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Saad Saeed AlamriResearch Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Jehan Saad M AlrahimiDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Saeedah Hamdan Al-JadaniDepartment of Basic Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, Saudi Arabia.
Al Baha University · SAKing Fahd Medical City · SAKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic adenosine monophosphate (cAMP) and calcium ions (Ca

Indexed as

cAMP, cyclic adenosine monophosphatecAMP signalingCell secretionCn, calcineurinCREB, cAMP-responsive element-binding proteinIntercellular communicationNFAT, nuclear factor of activated T-cellsPKA, protein kinase APP2BPP, protein phosphataseProtein kinases/phosphatasesROS, reactive oxygen speciesRyR, ryanodine receptor

Identifiers

PMID33424288
PMCPMC7783665
OpenAlexW3082977571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.