Evidence map›Paper›PMID 33424261›Full record

ReviewSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020

A review on genus

Rasmita Jena, Diptirani Rath, Sudhanshu Sekhar Rout, Durga Madhab Kar

Abstract readReview
In one paragraph

Review in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Antiviral Rotenoids and Isoflavones Isolated fromJournal of natural products · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Cytotoxicity ofMolecules (Basel, Switzerland) · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rasmita JenaDepartment of Pharmacology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar 751003, India.
Diptirani RathDepartment of Pharmacology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar 751003, India.
Sudhanshu Sekhar RoutDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar 751003, India.
Durga Madhab KarDepartment of Pharmacology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar 751003, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus Millettia belongs to Fabaceae includes 200 species which are distributed in tropical and subtropical regions of the world. Plants belong to this genus are used as folkloric medicine, for the treatment of different ailments like in wound healing, boil, sores, skin diseases, snake bite, muscle aches, pains, rheumatic arthritis, and gynaecological diseases. The aim of the review is to provide updated, comprehensive and categorized information on the aspects of ethnobotanical, phytochemical, pharmacological uses and toxicity of genus Millettia in order to identify their therapeutic potential and generate space for future research opportunities. The present study comprises of isolated flavonoids, phenolic compounds, phytosterols, saponins, alkaloids, polysaccharides, terpenoids and resins and pharmacological activities of various Millettia species. The relevant data were searched by using the keyword "Millettia" in different scientific databases like, "Google Scholar"; "NISCAIR repository"; "Pub Med"; "Science Direct"; "Scopus" and the taxonomy is validated by "The Plant List". This review discusses the existing information of the traditional evaluation as well as phytochemical and pharmacological evaluation of the extract and active constituents of the genus "Millettia". This review confirms that several Millettia species have emerged as a high-quality medicine in a traditional system for arthritis, wound healing, inflammation, skin diseases. Numerous conventional uses of Millettia species have been validated by modern pharmacology research. Intensive investigations of the genus Millettia relating to phytochemistry and pharmacology, especially their mechanism of action, safety, and efficacy could be the future research interests by the researcher in the area of phytomedicine.

Indexed as

Biological activitiesCH2Cl2, dichloromethaneChemical constituentsCNS, central nervous systemCOX-2, cyclooxygenase-2COX, cycloxygenaseDPPH, 2,2-diphenyl-picyrlhydrazylEthnomedicineEtOAc, ethyl acetateFabaceaeHCT116, colon cancerHepG2, hepatocellular carcinomaIL-6, interleukiniNOS, inducible nitric oxide synthaseKG-1, acute myelogenous leukemia cell lineLPS, lipopolysaccharideMCF7, breast cancer cell lineMDR, multidrug resistanceMeOH, CH3OH, methanolMIC, minimum inhibitory concentrationMillettiaMTT assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromiden-BuoH, n-butanolNO, nitric oxideORAC assay, oxygen radical absorption capacityRaji, lymphoma cell lineSRA, scavenger receptor type A and GR, glucagon receptorTLR4, toll-like receptor4TNF-α, tumour necrosis factor

Identifiers

PMID33424261
PMCPMC7783215

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.