Evidence map›Paper›PMID 33424253›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020

Differential modulation of Ahr and Arid5a: A promising therapeutic strategy for autoimmune encephalomyelitis.

Abdullah Alzahrani, Hamza Hanieh

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  7. Article
  8. Phytochemicals FromFrontiers in nutrition · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Abdullah AlzahraniBiological Sciences Department, King Faisal University, Al-Ahsa, Hofouf, Saudi Arabia.
Hamza HaniehBiological Sciences Department, King Faisal University, Al-Ahsa, Hofouf, Saudi Arabia.
Al-Hussein Bin Talal University · JOKing Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is an autoimmune disease that involves demyelination of axons in the central nervous system (CNS) and affects patients worldwide. It has been demonstrated that ligand-activated aryl hydrocarbon receptor (Ahr) ameliorates experimental autoimmune encephalomyelitis (EAE), a murine model of MS, by increasing CD4

Indexed as

3′UTR, 3′ untranslated regionActinD, actinomycin DAhrAhr, aryl hydrocarbon receptorArid5aArid5a, AT-rich interactive domain-containing protein 5aArnt, Ahr nuclear translocatorAutoimmunityCFA, complete Freund's adjuvantCNS, central nervous systemEAE, experimental autoimmune encephalomyelitisInflammationLPS, lipopolysaccharidemiR, microRNAMOG35-55, myelin oligodendrocyte glycoproteinMS, multiple sclerosisMultiple sclerosisPAS-A and PAS-B, Per-Arnt-Sim domainRBP, RNA-binding proteinRIP, RNA immunoprecipitationSPF, specific pathogen-freeTherapeutic

Identifiers

PMID33424253
PMCPMC7783111
OpenAlexW3097455482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.