Evidence map›Paper›PMID 33424251›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020

Identification of potential inhibitors of Zika virus NS5 RNA-dependent RNA polymerase through virtual screening and molecular dynamic simulations.

Noreen, Roshan Ali, Syed Lal Badshah, Muhammad Faheem, Sumra Wajid Abbasi, Riaz Ullah, Ahmed Bari, Syed Babar Jamal, Hafiz Majid Mahmood, Adnan Haider and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Alkaloids as potential antivirals. A comprehensive review.Natural products and bioprospecting · 2023
    Review
  4. F1000Research · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Discovery of Bispecific Lead Compounds fromMolecules (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Antiviral activities of flavonoids.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

NoreenInstitute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Roshan AliInstitute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Syed Lal BadshahDepartment of Chemistry, Islamia College University, Peshawar, Pakistan.
Muhammad FaheemDepartment of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Sumra Wajid AbbasiDepartment of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Riaz UllahDepartment of Pharmacognosy (MAPPRC), College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ahmed BariDepartment of Pharmacuitcal Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Syed Babar JamalDepartment of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Hafiz Majid MahmoodDepartment of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Adnan HaiderDepartment of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Sajjad HaiderDepartment of Chemical Engineering, College of Engineering, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SANational University of Medical Sciences · PKIslamia College University · PKKhyber Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) is one of the mosquito borne flavivirus with several outbreaks in past few years in tropical and subtropical regions. The non-structural proteins of

Indexed as

Binding free energyDocking studiesMolecular dynamicsNS5 RNA-dependent RNA polymeraseVirtual screeningZika virus

Identifiers

PMID33424251
PMCPMC7783101
OpenAlexW3094187867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.