ArticleSoa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry2021
Association between Maternal Adverse Childhood Experiences and Attention-Deficit/Hyperactivity Disorder in the Offspring: The Mediating Role of Antepartum Health Risks.
Article in Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- The Impact of Childhood Trauma on Neuropsychological Disorders and Its Intergenerational Transmission Mechanisms.Behavioral sciences (Basel, Switzerland) · 2026Review
- [Research progress on the mechanism of the impact of maternal childhood trauma on intergenerational transmission].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Maternal and Paternal Adverse Childhood Experiences (ACEs) and Offspring Health and Wellbeing: A Scoping Review.Maternal and child health journal · 2024Article
- Maternal childhood trauma and perinatal distress are related to infants' focused attention from 6 to 18 months.Scientific reports · 2021Article
- The Impact of Maternal Adverse Childhood Experiences on Offspring's Internalizing and Externalizing Problems.Psychiatry investigation · 2021Article
- Maternal Experiences of Trauma and Toddler Multisensory Attention Skills in a South African Community Cohort.Infancy : the official journal of the International Society on Infant StudiesArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to examine the effect of maternal adverse childhood experiences (ACEs) on the attention-deficit/hyper-activity disorder (ADHD) symptoms in the offspring and to examine the mediating role of antepartum health risk on the intergenera-tional transmission of maternal ACEs.
methodsThe participants consisted of 461 mother-child dyads. Mothers completed the ACEs questionnaire and Diagnostic Predictive Scales. Multivariate logistic regression analysis was used to estimate the risk of ADHD symptoms in the offspring of mothers with ACEs and the mediating effect of antepartum health risks by path analysis.
resultsIn all, 35.4% (n=163) had at least one maternal ACE, and 11.1% (n=51) had three or more. Compared to the non-ADHD symp-tom group, the group of offspring with ADHD symptoms showed a significant association with maternal ACE score (p<0.001) and an-tepartum health risks (p<0.001). Multivariate analysis further showed a significant association between the sum of maternal ACEs [odds ratio (OR)=1.264, 95% confidence interval (CI)= 1.060-1.516, p=0.009], antepartum health risks (OR=1.236, 95% CI=1.036-1.475, p= 0.019), and ADHD symptoms in the offspring. In the mediation model in which the mother's ACE score affected the offspring's ADHD symptoms, partial mediation through antepartum health risks was found to be significant (B=0.041, 95% CI=0.011-0.124).
conclusionMaternal ACEs are significantly related to the incidence of ADHD symptoms in the offspring and antepartum health risks exert an indirect effect. These findings suggest that maternal ACEs have a negative impact on the offspring's brain development through intergenerational transmission, resulting in neurodevelopmental disorders such as ADHD.
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