Evidence map›Paper›PMID 33424210›Full record

ArticleInfectious diseases in clinical practice (Baltimore, Md.)2020

A Single-Center Experience and Literature Review of Management Strategies for

Aneela Majeed, Marti M Larriva, Ahmad Iftikhar, Adeela Mushtaq, Patrick Campbell, Mustafa Nadeem Malik, Abdul Rafae, Muhammad Abu Zar, Ahmad Kamal, Midhat Lakhani and 3 more

Open access · greenAbstract read
In one paragraph

Article in Infectious diseases in clinical practice (Baltimore, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Prevalence ofFrontiers in cellular and infection microbiology · 2022
    Pooled it
  2. Review
  3. Epidemiology and Outcomes of RecurrentOpen forum infectious diseases · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Aneela MajeedDepartment of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA.
Marti M LarrivaDepartment of Pharmacy, University of Arizona, Tucson, AZ.
Ahmad IftikharDepartment of Medicine, University of Arizona, Tucson, AZ.
Adeela MushtaqDepartment of Medicine, University of Pittsburgh Medical Center, McKeesport, PA.
Patrick CampbellDepartment of Pharmacy, University of Arizona, Tucson, AZ.
Mustafa Nadeem MalikDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Abdul RafaeDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Muhammad Abu ZarDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Ahmad KamalDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Midhat LakhaniDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Nageena Rani KhalidDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
Tirdad T ZangenehDepartment of Medicine, Division of Infectious Diseases, University of Arizona, Tucson, AZ.
Faiz AnwerDepartment of Medicine, Division of Hematology and Oncology, University of Arizona, Tucson, AZ 85724.
University of Arizona · USStanford University · USJacobi Medical Center · USMcLaren Regional Medical Center · USPalmetto Hematology Oncology · USSUNY Downstate Health Sciences University · USUniversity of Pittsburgh Medical Center · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
NCI NIH HHS P30 CA023074
6 · The paper itself

Abstract

introductionThe aim of our study is to evaluate risk factors associated with the development of

methodsWe performed a retrospective review of medical records of adult HSCT recipients diagnosed between 2013 and 2016 at our center. Logistic regression models were used to determine the relationship between risk factors and the odds of CDI.

resultsThe overall incidence of CDI in HSCT patients was 9.4%. The incidence of CDI was higher in allogeneic HSCT (20%) versus autologous HSCT (4.8%). No statistically significant differences in age, gender, cancer type, transplant type were found between those who developed CDI and those who did not. However, patients with CDI had a longer length of stay (25 days) and used more antibiotics (30 days prior to and during admission for HSCT) than non-CDI patients (19 days). Only two of 17 patients (11.8%) with CDI experienced recurrence among 180 patients after HSCT. No patient suffered from toxic megacolon or ileus and no patient underwent colectomy. There was no mortality associated with CDI at our center.

conclusionCDI has an incidence rate of 9.4% in HSCT recipients. Established risk factors including age, gender, cancer type, and transplant type were not identified as risk factors in our population. However, longer LOS and use of greater than four lines of antibiotics were observed among those with CDI compared to those without CDI.

Indexed as

allogenic hematopoietic stem cell transplantautologous hematopoietic stem cell transplantClostridium difficile

Identifiers

PMID33424210
PMCPMC7792527
OpenAlexW2987689574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.