Evidence map›Paper›PMID 33423696›Full record

ArticleJournal of cheminformatics2021

COCONUT online: Collection of Open Natural Products database.

Maria Sorokina, Peter Merseburger, Kohulan Rajan, Mehmet Aziz Yirik, Christoph Steinbeck

Abstract read
In one paragraph

Article in Journal of cheminformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 257 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
257citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

257 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. ManagingMolecules (Basel, Switzerland) · 2025
    Pooled it
  2. Review
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  4. Article
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  7. Mapping Evolution of Molecules across Biochemistry with Assembly Theory.Journal of chemical information and modeling · 2026
    Article
  8. Article
  9. Article
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  11. Review
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  14. Rambutan (Molecules (Basel, Switzerland) · 2026
    Article
  15. Review
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  17. Article
  18. Article
  19. Review
  20. Article

197 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria SorokinaInstitute for Inorganic and Analytical Chemistry, University Friedrich-Schiller, Lessing Strasse 8, 07743, Jena, Germany. maria.sorokina@uni-jena.de.ORCID http://orcid.org/0000-0001-9359-7149
Peter MerseburgerInstitute for Inorganic and Analytical Chemistry, University Friedrich-Schiller, Lessing Strasse 8, 07743, Jena, Germany.ORCID http://orcid.org/0000-0002-5154-8696
Kohulan RajanInstitute for Inorganic and Analytical Chemistry, University Friedrich-Schiller, Lessing Strasse 8, 07743, Jena, Germany.ORCID http://orcid.org/0000-0003-1066-7792
Mehmet Aziz YirikInstitute for Inorganic and Analytical Chemistry, University Friedrich-Schiller, Lessing Strasse 8, 07743, Jena, Germany.ORCID http://orcid.org/0000-0001-7520-7215
Christoph SteinbeckInstitute for Inorganic and Analytical Chemistry, University Friedrich-Schiller, Lessing Strasse 8, 07743, Jena, Germany.ORCID http://orcid.org/0000-0001-6966-0814

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are bioactive. This potential raised great interest in NP research around the world and in different application fields, therefore, over the years a multiplication of generalistic and thematic NP databases has been observed. However, there is, at this moment, no online resource regrouping all known NPs in just one place, which would greatly simplify NPs research and allow computational screening and other in silico applications. In this manuscript we present the online version of the COlleCtion of Open Natural prodUcTs (COCONUT): an aggregated dataset of elucidated and predicted NPs collected from open sources and a web interface to browse, search and easily and quickly download NPs. COCONUT web is freely available at https://coconut.naturalproducts.net .

Indexed as

DatabaseMolecular similarity searchMolecular substructure searchMongoDBNatural productsNoSQL

Identifiers

PMID33423696
PMCPMC7798278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.