ArticleAcute and critical care2020
Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study.
Article in Acute and critical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07098611 (A New Tool for Extubation Readiness in Mechanically Ventilated Patients), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score (REXs STUDY)
Who cites it
4 citing papers in PubMed, 15 citations in OpenAlex.
- Intensive Management of a Patient with HIV, Active Tuberculosis, and COVID-19: A Multidisciplinary Approach in the Intensive Care Unit.Life (Basel, Switzerland) · 2025Article
- Pendelluft as a predictor of weaning in critically ill patients: An observational cohort study.Frontiers in physiology · 2023Article
- Biosignal-Based Digital Biomarkers for Prediction of Ventilator Weaning Success.International journal of environmental research and public health · 2021Article
- Exploring Extubation Readiness in Guillain-Barré Syndrome: A Case Report and Literature Review.Journal of investigative medicine high impact case reportsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients.
methodsA cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16-70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated.
resultsThe success rate of the entire weaning process was 67.2% (43/64). The median NIF values were -26.0 cm H2O (interquartile range [IQR], -28.0 to -25.0) in the successful weaning group and -24.0 cm H2O (IQR, -25.0 to -23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤-25 cm H2O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV.
conclusionsAn NIF cutoff threshold ≤-25 cm H2O can be used as predictor of weaning success in Vietnamese surgical intensive care patients.
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