Evidence map›Paper›PMID 33423353›Full record

ArticleClinical transplantation2021

African Americans' discussions about living-donor kidney transplants with family or friends: Who, what, and why not?

Nicole DePasquale, Matthew J Ellis, Debra L Sudan, Patti L Ephraim, Lisa M McElroy, Dinushika Mohottige, Clemontina A Davenport, Xiyuan Zhang, Sarah B Peskoe, Tara S Strigo and 5 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06182475 (Increasing Equity in Live Donor Kidney Transplantation Through Effective Patient-Provider Communication), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06182475 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Increasing Equity in Live Donor Kidney Transplantation Through Effective Patient-Provider Communication

TypeinterventionalSponsorTemple UniversityRan2026 to 2027Enrolled70ConditionsKidney Disease, Chronic, End Stage Renal Disease, Kidney ReplacementArmsEPPComm Provider Training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The Determinants and Consequences of Living Donor Discussion Direction.Progress in transplantation (Aliso Viejo, Calif.) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Nicole DePasqualeDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.ORCID 0000-0003-2638-0390
Matthew J EllisDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Debra L SudanDivision of Abdominal Transplant Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Patti L EphraimWelch Center for Prevention, Epidemiology and Clinical Research, Baltimore, MD, USA.
Lisa M McElroyDivision of Abdominal Transplant Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.ORCID 0000-0003-2366-2579
Dinushika MohottigeDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.ORCID 0000-0001-5099-4910
Clemontina A DavenportDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Xiyuan ZhangDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Sarah B PeskoeDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Tara S StrigoDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.
Ashley N CabacunganDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.
Iris PoundsDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.
Jennie A RileyDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.
Margaret FalkovicDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.
L Ebony BoulwareDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-8650-4212
Duke University · USJohns Hopkins University · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Transplant Social Worker Support for Live Kidney Donation in African AmericansR01DK098759 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2012 to 2016
$1.5M
NCATS NIH HHS UL1 TR002553NIDDK NIH HHS R01 DK098759
6 · The paper itself

Abstract

backgroundAlthough discussions with family or friends can improve access to living-donor kidney transplantation (LDKT), they remain an understudied step in the LDKT process.

methodsAmong 300 African American transplant candidates, we examined how sociodemographic, clinical, LDKT-related, and psychosocial characteristics related to the occurrence of LDKT discussions with family or friends. We also analyzed the relation between discussion occurrence and donor activation on transplant candidates' behalves (at least one donor inquiry or completed donor evaluation in the medical record). We assessed associations of discussion characteristics (context, content, and perceptions) with donor activation among discussants, and we identified discussion barriers among non-discussants.

resultsMost candidates (90%) had discussed LDKT. Only family functioning was statistically significantly associated with discussion occurrence. Specifically, family dysfunction was associated with 62% lower odds of discussion than family function. Family functioning, discussion occurrence, and different discussion characteristics were statistically significantly related to donor activation. The most prevalent discussion barrier was never having thought about discussing LDKT.

conclusionsFamily functioning affected the likelihood of discussing LDKT, and family functioning, discussion occurrence, and discussion characteristics were associated with donor activation. Advancing understanding of how family functioning and LDKT discussions affect progression to LDKT may benefit interventions to increase LDKT.

Indexed as

Kidney TransplantationBlack or African AmericanFriendsHumansKidneyLiving Donorscommunicationdiscussion barriersdonor activationliving kidney donation

Identifiers

PMID33423353
PMCPMC8809139
OpenAlexW3120346010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.