Evidence map›Paper›PMID 33423115›Full record

ReviewJournal of experimental orthopaedics2021

A narrative review of the last decade's literature on the diagnostic accuracy of septic arthritis of the native joint.

Elizabeth H G Turner, Mc Daniel H Lang, Andrea M Spiker

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of experimental orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Impact of septic arthritis on quality of life: arthroscopy vs. arthrotomy.Archives of orthopaedic and trauma surgery · 2025
    Article
  8. Effect of Preoperative Antibiotic Therapy on Operative Culture Yield for Diagnosis of Native Joint Septic Arthritis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  9. Article
  10. Enhancing Diagnostics in Orthopedic Infections.Journal of clinical microbiology · 2022
    Review
  11. Staphylococcus aureus-induced septic arthritis of the ankle related to malum perforans in a diabetes patient.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth H G TurnerDepartment of Orthopedics and Rehabilitation, University of Wisconsin - Madison, UW Health at The American Center, 4602 Eastpark Blvd., Madison, WI, 53718, USA.
Mc Daniel H LangDepartment of Orthopedics and Rehabilitation, University of Wisconsin - Madison, UW Health at The American Center, 4602 Eastpark Blvd., Madison, WI, 53718, USA.
Andrea M SpikerDepartment of Orthopedics and Rehabilitation, University of Wisconsin - Madison, UW Health at The American Center, 4602 Eastpark Blvd., Madison, WI, 53718, USA. spiker@ortho.wisc.edu.ORCID http://orcid.org/0000-0003-1243-9726
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While septic arthritis can be a straightforward diagnosis, there are many cases when the diagnosis is difficult to make. The aim of this study was to review the last decade's literature on the diagnosis of septic arthritis of the native joint in adults and summarize that data in an easy to follow algorithm to clarify how the last decade's data may be applied to the diagnosis of septic arthritis. A search of PubMed and CINAHL databases was performed to identify studies that compared results diagnostic tests for septic arthritis. We cross referenced this search with searches of additional databases (including Cochrane Library and Scopus) to confirm similar search results. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool was used by two independent reviewers to determine study quality and risk of bias. After applying inclusion and exclusion criteria to the initial search, 15 papers total were included for analysis. All 15 papers were of high quality methodology as determined by the QUADAS tool. There were 26 different diagnostics tests used across the 15 papers included for review. Three of those diagnostic tests had specificity and sensitivity greater than 80%. Eight tests had a positive likelihood ratio of ≥10. Three tests had a negative likelihood ratio < 0.1, indicating that they may help to rule out septic arthritis. A flowchart was created to summarize the findings of our review, so that physicians may reference this visual in making the appropriate diagnosis when the commonly held standards of cell count, gram stain, and culture aren't enough to make the diagnosis.

Indexed as

Joint aspirationSeptic arthritisSeptic joint

Identifiers

PMID33423115
PMCPMC7797010
OpenAlexW3119676804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.