Evidence map›Paper›PMID 33423107›Full record

ReviewCell and tissue banking2021

The storage of skull bone flaps for autologous cranioplasty: literature review.

Vicente Mirabet, Daniel García, Nuria Yagüe, Luis Roberto Larrea, Cristina Arbona, Carlos Botella

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Cell and tissue banking, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07183540 (Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07183540 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery: a Multicenter, Prospective, Open-label, Endpoint-blinded, Randomized Controlled Study

TypeinterventionalSponsorThe Affiliated Hospital Of Guizhou Medical UniversityRan2025 to 2027Enrolled582ConditionsCranial DefectArmsoperation opportunity-within 6 weeks after the DC operation., operation opportunity-within 90 to 180 days after the DC operation.
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cranial Repair in Children: Techniques, Materials, and Peculiar Issues.Advances and technical standards in neurosurgery · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vicente MirabetCell and Tissue Bank, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain. mirabet_vic@gva.es.
Daniel GarcíaService of Neurosurgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Nuria YagüeCell and Tissue Bank, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Luis Roberto LarreaCell and Tissue Bank, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Cristina ArbonaCell and Tissue Bank, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Carlos BotellaService of Neurosurgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of autologous bone flap for cranioplasty after decompressive craniectomy is a widely used strategy that allows alleviating health expenses. When the patient has recovered from the primary insult, the cranioplasty restores protection and cosmesis, recovering fluid dynamics and improving neurological status. During this time, the bone flap must be stored, but there is a lack of standardization of tissue banking practices for this aim. In this work, we have reviewed the literature on tissue processing and storage practices. Most of the published articles are focused from a strictly clinical and surgical point of view, paying less attention to issues related to tissue manipulation. When bone resorption is avoided and the risk of infection is controlled, the autograft represents the most efficient choice, with the lowest risk of complication. Otherwise, depending on the degree of involvement, the patient may have to undergo new surgery, assuming further risks and higher healthcare costs. Therefore, tissue banks must implement protocols to provide products with the highest possible clinical effectiveness, without compromising safety. With a centralised management of tissue banking practices there may be a more uniform approach, thus facilitating the standardization of procedures and guidelines.

Indexed as

Bone ResorptionDecompressive CraniectomyPlastic Surgery ProceduresHumansPostoperative ComplicationsRetrospective StudiesSkullSurgical FlapsAutologous bone flapBone infectionBone resorptionCranioplastyDecompressive craniectomyStorageTissue banking

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.