Evidence map›Paper›PMID 33423055›Full record

SynthesisAmerican journal of epidemiology2021

Is the US Gender Gap in Depression Changing Over Time? A Meta-Regression.

Jonathan M Platt, Lisa Bates, Justin Jager, Katie A McLaughlin, Katherine M Keyes

Abstract readMeta-Analysis
In one paragraph

Synthesis in American journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The role of pubertal development in the association between trauma and internalising symptoms in female youth.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Exploring Self-Care, Anxiety, Depression, and the Gender Gap in the Software Engineering Pipeline.International journal of environmental research and public health · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jonathan M Platt
Lisa Bates
Justin Jager
Katie A McLaughlin
Katherine M Keyes

Funding

Neurodevelopmental Mechanisms Underlying Stress Vulnerability during AdolescenceR37MH119194 · NIMH · HARVARD UNIVERSITY · PI Katie McLaughlin · 2020 to 2026
$10.6M
Child Trauma and the Development of Neural Systems Underlying Emotion RegulationR01MH103291 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2014 to 2018
$3.8M
Deprivation and Threat: Dimensions of Early Experience and Neural DevelopmentR01MH106482 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2016 to 2020
$3.1M
Age, period, and cohort effects on gender differences in alcohol use and alcohol use disorders in 47 national, longitudinally-followed cohortsR01AA026861 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JAGER, JUSTIN O, KEYES, KATHERINE M. · 2018 to 2022
$1.9M
NIAAA NIH HHS R01 AA026861NIMH NIH HHS R01 MH103291NIMH NIH HHS R01 MH106482NIMH NIH HHS R37 MH119194
6 · The paper itself

Abstract

The depression gap refers to higher rates of depression among women than men. Change in the depression gap over time might elucidate social causes of this disparity-such as unequal college attendance or employment status. We conducted a meta-regression analysis to estimate variation in the depression gap over time by age, accounting for potential sources of variation between studies. Electronic databases and bibliographies were searched for English-language studies from January 1980 through October 2019; 144 independent estimates from US-representative samples met selection criteria (n = 813,189). The depression gap was summarized as prevalence ratios among studies using diagnostic instruments and as standardized mean differences among symptom-based studies. Primary study measures were baseline study year (range, 1982-2017) and age (age groups ranging, in years, from 10-59 and 60 or older). Compared with respondents aged ≥60 years, depression prevalence was greater among respondents aged 10-19 (prevalence ratio = 1.26, 95% confidence interval: 1.02, 1.56). Over time, the depression gap did not change among adults, but it increased among adolescents (age-by-time interaction prevalence ratio = 1.05, 95% confidence interval: 1.01, 1.08). Results were similar for symptom-based studies. The present study finds no evidence of a change in the depression gender gap for US adults; however, the gap increased among adolescents. Greater attention to factors driving this widening disparity in adolescent depression is needed.

Indexed as

Health Status DisparitiesSex FactorsAdolescentAdultChildDepressionFemaleHumansMaleMiddle AgedPrevalenceRegression AnalysisUnited StatesYoung Adultdepressiondepressive symptomsgenderhealth disparitiestime trendsUnited States

Identifiers

PMID33423055
PMCPMC8484777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.