Evidence map›Paper›PMID 33422809›Full record

ArticleJournal of critical care2021

Provision of acute renal replacement therapy, using three separate modalities, in critically ill patients during the COVID-19 pandemic. An after action review from a UK tertiary critical care centre.

Richard Fisher, Jonathan Clarke, Khaled Al-Arfi, Rohit Saha, Eirini Lioudaki, Reena Mehta, Clemens Pahl, Claire Sharpe, Kate Bramham, Sam Hutchings

Open access · greenAbstract read
In one paragraph

Article in Journal of critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Richard FisherDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: richard.fisher8@nhs.net.
Jonathan ClarkeDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: jonathan.clarke10@nhs.net.
Khaled Al-ArfiDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: khaled.alarfi@nhs.net.
Rohit SahaDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: rohit.saha@nhs.net.
Eirini LioudakiKing's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: eirini.lioudaki1@nhs.net.
Reena MehtaDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: reena.mehta@nhs.net.
Clemens PahlDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: clemenspahl@nhs.net.
Claire SharpeKing's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: claire.sharpe1@nhs.net.
Kate BramhamKing's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: kate.bramham@nhs.net.
Sam HutchingsDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: sam.hutchings@nhs.net.
King's College Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to describe the incidence of Acute Kidney Injury (AKI) amongst patients admitted to the Intensive Care Unit (ICU) with COVID-19. In addition we aim to detail the range of Renal Replacement Therapy (RRT) modalities offered to these patients (including peritoneal dialysis - PD - and intermittent haemodialysis - IHD) in order to meet demand during pandemic conditions. MATERIALS AND

methodsSingle-centre retrospective case note review of adult patients with confirmed COVID-19 admitted to ICU.

resultsAmongst 136 patients without a prior history of End Stage Kidney Disease (ESKD), 108 (79%) developed AKI and 63% of admitted patients received RRT. Due to resource limitations the range of RRT options were expanded from solely Continuous Veno-Venous HaemoDiaFiltration (CVVHDF - our usual standard of care) to include PD (in 35 patients) and IHD (in 15 patients). During the study period the proportion of RRT provided within ICU as CVVHDF fell from 100% to a nadir of 39%. There were no significant complications of either PD or IHD.

conclusionsDuring periods of resource limitations PD and IHD can safely be used to reduce dependence on CVVHDF in select patients with AKI secondary to COVID-19.

Indexed as

Acute Kidney InjuryAdultAgedContinuous Renal Replacement TherapyCOVID-19Critical CareFemaleHumansIntensive Care UnitsIntermittent Renal Replacement TherapyMaleMiddle AgedPeritoneal DialysisRenal Replacement TherapyRetrospective StudiesSARS-CoV-2Acute kidney injuryCOVID-19HaemodialysisPeritoneal DialysisRenal replacement therapy

Identifiers

PMID33422809
PMCPMC7837302
OpenAlexW3115274684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.