Evidence map›Paper›PMID 33422726›Full record

ArticleJournal of biomechanics2021

Effect of simulated rehabilitation on hip joint loading during single limb squat in patients with hip dysplasia.

Brecca M M Gaffney, Marcie Harris-Hayes, John C Clohisy, Michael D Harris

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
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  8. Article
  9. Elevated loading at the posterior acetabular edge of dysplastic hips during double-legged squat.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  10. The biomechanical disadvantage of dysplastic hips.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brecca M M GaffneyProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
Marcie Harris-HayesProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, United States; Department of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
John C ClohisyDepartment of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
Michael D HarrisProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, United States; Department of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, United States; Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, United States. Electronic address: harrismi@wustl.edu.
Washington University in St. Louis · US

Funding

Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Muscle Geometry and its Influence on Function in Patients with Developmental Dysplasia of the HipK01AR072072 · NIAMS · WASHINGTON UNIVERSITY · PI HARRIS, MICHAEL D · 2018 to 2022
$554k
Effects of Simulated Interventions on Hip Articular Cartilage Loading in Patients with Femoroacetabular Impingement and Developmental Dysplasia of the HipF32AR075349 · NIAMS · WASHINGTON UNIVERSITY · PI GAFFNEY, BRECCA · 2019 to 2020
$97k
NIAMS NIH HHS F32 AR075349NIAMS NIH HHS K01 AR072072NIAMS NIH HHS P30 AR074992NICHD NIH HHS T32 HD007434
6 · The paper itself

Abstract

Rehabilitation for patients with developmental dysplasia of the hip (DDH) addresses modifiable factors in an effort to reduce symptoms and prevent or delay the development of osteoarthritis, yet its effect on joint mechanics remains unknown. Our objective was to establish how rehabilitation (muscle strengthening and movement training), simulated with a musculoskeletal model and probabilistic analyses, alters hip joint reaction forces (JRF) in patients with DDH during a single limb squat. In four patients with DDH, hip abductor strengthening was simulated by increasing the maximum isometric force value between 0 and 32.6% and movement training was simulated by decreasing the hip adduction angle between 0 and 10° relative to baseline. 2,000 Monte Carlo simulations were performed separately to simulate strengthening and movement training, from which 99% confidence bounds and sensitivity factors were calculated. Our results indicated that simulated movement training aimed at decreasing hip adduction had a substantially larger influence on hip JRF than strengthening, as indicated by 99% confidence bounds of the resultant JRF (0.88 ± 0.55 xBW vs. 0.31 ± 0.12 xBW, respectively). Relative to baseline, movement training that resulted in a 10° decrease in hip adduction decreased the resultant JRF by 0.78 ± 0.65 xBW, while strengthening the abductors by 17.6% increased resultant JRF by 0.18 ± 0.06 xBW. To our knowledge, these results are the first to provide evidence pertaining to the effect of rehabilitation on joint mechanics in patients with DDH and can be used to inform more targeted interventions.

Indexed as

Hip DislocationBiomechanical PhenomenaHip JointHumansMechanical PhenomenaPostureHip dysplasiaMusculoskeletal modelingProbabilistic analysisRehabilitation

Identifiers

PMID33422726
PMCPMC7938363
OpenAlexW3119151349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.