Evidence map›Paper›PMID 33422589›Full record

ArticleThe Journal of hospital infection2021

Cross-sectional prevalence of SARS-CoV-2 antibodies in healthcare workers in paediatric facilities in eight countries.

D Goldblatt, M Johnson, O Falup-Pecurariu, I Ivaskeviciene, V Spoulou, E Tamm, M Wagner, H J Zar, L Bleotu, R Ivaskevicius and 7 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of hospital infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Seroprevalence of SARS-CoV-2 Antibodies in Africa: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Socioeconomic and Demographic Risk Factors for SARS-CoV-2 Seropositivity Among Healthcare Workers in a UK Hospital: A Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Observational
  3. Determinants of seropositivity for SARS-CoV-2 in hospital staff in the second wave of the pandemic in Slovenia.International journal of occupational medicine and environmental health · 2022
    Article
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  13. SARS-CoV-2 infection in public hospital medical doctors in an Eastern Cape metro.Southern African journal of infectious diseases · 2022
    Article
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  15. Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Workers in South Africa: A Longitudinal Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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  16. Article
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  19. Article
  20. Antibody Responses in COVID-19: A Review.Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 8 countries.

D GoldblattGreat Ormond Street Institute of Child Health, University College London, London, UK; Great Ormond Street Children's Hospital NHS Foundation Trust, London, UK. Electronic address: d.goldblatt@ucl.ac.uk.
M JohnsonGreat Ormond Street Institute of Child Health, University College London, London, UK.
O Falup-PecurariuChildren's Clinic Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania.
I IvaskevicienePaediatric Centre, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania.
V Spoulou'Agia Sophia' Children's Hospital of Athens, Athens, Greece.
E TammChildren's Clinic of Tartu University Hospital, Tartu, Estonia.
M WagnerDivision of Neonatology, Paediatric Intensive Care and Neuropaediatrics, Department of Paediatrics, Comprehensive Centre for Paediatrics, Medical University of Vienna, Vienna, Austria.
H J ZarDepartment of Paediatrics and Child Health, Red Cross Children's Hospital, and SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
L BleotuChildren's Clinic Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania.
R IvaskeviciusPaediatric Centre, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania.
I PapadatouImmunobiology and Vaccinology Research Laboratory, National and Kapodistrian University of Athens, Athens, Greece.
P JõgiChildren's Clinic of Tartu University Hospital, Tartu, Estonia.
J LischkaClinical Division of Paediatric Pulmonology, Allergology and Endocrinology, Department of Paediatrics and Adolescent Medicine, Comprehensive Centre for Paediatrics, Medical University of Vienna, Vienna, Austria.
Z Franckling-SmithDepartment of Paediatrics and Child Health, Red Cross Children's Hospital, and SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
D IsarovaChildren's Clinical University Hospital, Riga, Latvia.
L GrandjeanGreat Ormond Street Institute of Child Health, University College London, London, UK; Great Ormond Street Children's Hospital NHS Foundation Trust, London, UK.
D ZavadskaChildren's Clinical University Hospital, Riga, Latvia.
Children's Clinical University Hospital · LVMedical University of Vienna · ATTartu University Hospital · EETransylvania University of Brașov · ROUniversity of Cape Town · ZAVilnius University · LTChildren's Hospital Agia Sophia · GRGreat Ormond Street Hospital · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBNational and Kapodistrian University of Athens · GRUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare workers (HCWs) have been disproportionately affected by coronavirus disease 2019 (COVID-19), which may be driven, in part, by nosocomial exposure. If HCW exposure is predominantly nosocomial, HCWs in paediatric facilities, where few patients are admitted with COVID-19, may lack antibodies to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and be at increased risk during the current resurgence.

aimTo compare the seroprevalence of SARS-CoV-2 amongst HCWs in paediatric facilities in seven European countries and South Africa (N=8).

methodsAll categories of paediatric HCWs were invited to participate in the study, irrespective of previous symptoms. A single blood sample was taken and data about previous symptoms were documented. Serum was shipped to a central laboratory in London where SARS-CoV-2 immunoglobulin G was measured.

findingsIn total, 4114 HCWs were recruited between 1

conclusionOverall seroprevalence amongst paediatric HCWs is similar to their national populations and linked to the national COVID-19 burden. Staff working in paediatric facilities in low-burden countries have very low seroprevalence rates and thus are likely to be susceptible to COVID-19. Their susceptibility to infection may affect their ability to provide care in the face of increasing cases of COVID-19, and this highlights the need for appropriate preventative strategies in paediatric healthcare settings.

Indexed as

AdultAgedAntibodies, ViralCOVID-19Cross-Sectional StudiesEuropeFemaleHealth PersonnelHospitals, PediatricHumansMaleMiddle AgedOccupational DiseasesPrevalenceRisk AssessmentSeroepidemiologic StudiesAntibodies, ViralCOVID-19Healthcare workersHospital workersSARS-CoV-2Seroprevalence

Identifiers

PMID33422589
PMCPMC7836791
OpenAlexW3120437704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.