Evidence map›Paper›PMID 33422143›Full record

Trial reportBMC research notes2021

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients.

Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J McElvaney, Oisín F McElvaney and 5 more

Registry-linked trialOpen access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC research notes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06181539 (Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With Acute Respiratory Distress Syndrome by Electrical Impedance Tomography), which is not on this map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06181539 completednot on this mapstarted 2023, after this paper: background citation

Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With Acute Respiratory Distress Syndrome by Electrical Impedance Tomography

TypeobservationalSponsorUnion Hospital, Tongji Medical College, Huazhong University of Science and TechnologyRan2023 to 2025Enrolled94ConditionsAcute Respiratory Distress Syndrome, Electrical Impedance Tomography, Prone Position Ventilation, Ventilation Perfusion Mismatch
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Review
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Prone positioning in COVID-19 ARDS: more pros than cons.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  13. Review
  14. PaOAcute medicine & surgery
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Jennifer ClarkeDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland.
Pierce GeogheganDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland.
Natalie McEvoyDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland.
Maria BoylanBeaumont Hospital, Dublin 9, Ireland.
Orna Ní ChoileáinBeaumont Hospital, Dublin 9, Ireland.
Martin MulliganBeaumont Hospital, Dublin 9, Ireland.
Grace HoganDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland.
Aoife KeoghDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland.
Oliver J McElvaneyBeaumont Hospital, Dublin 9, Ireland.
Oisín F McElvaneyBeaumont Hospital, Dublin 9, Ireland.
John BourkeGalway University Hospital, University Road, Galway, Ireland.
Bairbre McNicholasGalway University Hospital, University Road, Galway, Ireland.
John G LaffeyGalway University Hospital, University Road, Galway, Ireland.
Noel G McElvaneyBeaumont Hospital, Dublin 9, Ireland.
Gerard F CurleyDepartment of Anaesthesia and Critical Care, Royal College of Surgeons Ireland, Smurfit Building, Beaumont Hospital, Dublin 9, D09 YD60, Ireland. gercurley@rcsi.com.ORCID http://orcid.org/0000-0003-0271-195X
Beaumont Hospital · IERoyal College of Surgeons in Ireland · IEUniversity Hospital Galway · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS.

resultsThis was a prospective cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive, invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent prone positioning in ICU as part of their management. The main outcome was the effect of prone positioning on gas exchange and respiratory mechanics. There was a median improvement in the PaO

Indexed as

Prone PositionCohort StudiesCOVID-19HumansLungMaleMiddle AgedOxygenProspective StudiesRespiration, ArtificialOxygenAdultProne positionRespiratory distress syndromeSevere acute respiratory syndrome coronavirus 2

Identifiers

PMID33422143
PMCPMC7796647
OpenAlexW3118862266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.