Evidence map›Paper›PMID 33422032›Full record

ArticleBMC nephrology2021

Target value of mean arterial pressure in patients undergoing continuous renal replacement therapy due to acute kidney injury.

Yaerim Kim, Donghwan Yun, Soie Kwon, Kyubok Jin, Seungyeup Han, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Sejoong Kim and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yaerim KimDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Donghwan YunDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Soie KwonDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Kyubok JinDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Seungyeup HanDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Dong Ki KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Kwon Wook JooDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Yon Su KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea.
Sejoong KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea. sejoong@snubh.org.
Seung Seok HanDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, Korea. hansway80@gmail.com.ORCID 0000-0003-0137-5261
Seoul National University · KRKeimyung University · KRNew Generation University College · ET

Funding

National Research Foundation 2019R1A2C1085411
6 · The paper itself

Abstract

backgroundAlthough patients undergoing continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) frequently have instability in mean arterial pressure (MAP), no consensus exists on the target value of MAP related to high mortality after CRRT.

methodsA total of 2,292 patients who underwent CRRT due to AKI in three referral hospitals were retrospectively reviewed. The MAPs were divided into tertiles, and the 3

resultsThe mean value of MAP was 80.7 ± 17.3 mmHg at the time of CRRT initiation. The median intensive care unit stay was 5 days (interquartile range, 2-12 days), and during this time, 1,227 (55.5%) patients died. The 1

conclusionsLow MAP at CRRT initiation is associated with a high risk of mortality, particularly when it is < 82.7 mmHg. This value may be used for risk classification and as a potential therapeutic target.

Indexed as

Arterial PressureContinuous Renal Replacement TherapyAcute Kidney InjuryAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesAcute kidney injuryContinuous renal replacement therapyMean arterial pressureMortality

Identifiers

PMID33422032
PMCPMC7796677
OpenAlexW3120699611

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.