Evidence map›Paper›PMID 33421981›Full record

Observational studyCancer research and treatment2021

Development and Validation of a Symptom-Focused Quality of Life Questionnaire (KOQUSS-40) for Gastric Cancer Patients after Gastrectomy.

Bang Wool Eom, Joongyub Lee, In Seob Lee, Young-Gil Son, Keun Won Ryu, Sung Geun Kim, Hyoung-Il Kim, Young-Woo Kim, Seong-Ho Kong, Oh Kyoung Kwon and 25 more

Registry-linked trialAbstract readObservational StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07504913 (SPQUSS-41), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07504913 recruitingnot on this mapstarted 2025, after this paper: background citation

SPQUSS-41: Validación Del Cuestionario de Calidad de Vida KOQUSS-40 Para Los Pacientes Con gastrectomía Por cáncer gástrico [SPQUSS-41]

TypeobservationalSponsorParc de Salut MarRan2025 to 2026Enrolled505ConditionsStomach Neoplasms, Validation StudyArmsDevelopment Questionnaire and Validation Questionnaire
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
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  6. Long-term quality of life, financial toxicity, and decision regret following therapeutic and prophylactic gastrectomy for cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Bang Wool EomCenter for Gastric Cancer, National Cancer Center, Goyang, Korea.
Joongyub LeeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
In Seob LeeDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Young-Gil SonDepartment of Surgery, Keimyung University Dongsan Medical Center, Daegu, Korea.
Keun Won RyuCenter for Gastric Cancer, National Cancer Center, Goyang, Korea.
Sung Geun KimDepartment of Surgery, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyoung-Il KimDepartment of Surgery, Yonsei University Severance Hospital, Seoul, Korea.
Young-Woo KimCenter for Gastric Cancer, National Cancer Center, Goyang, Korea.
Seong-Ho KongDepartment Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University of College of Medicine, Seoul, Korea.
Oh Kyoung KwonDepartment of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Ji-Ho ParkDepartment of Surgery, Gyeongsang National University School of Medicine, Jinju, Korea.
Ji Yeong AnDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang Hyun KimDepartment of Surgery, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Byoung-Jo SuhDepartment of Surgery, Inje University Haeundae Paik Hospital, Busan, Korea.
Hong Man YoonCenter for Gastric Cancer, National Cancer Center, Goyang, Korea.
Myoung Won SonDepartment of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Ji Yeon ParkDepartment of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Jong-Min ParkDepartment of Surgery, National Medical Center, Seoul, Korea.
Sang-Ho JeongDepartment of Surgery, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Moon-Won YooDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Geum Jong SongDepartment of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Han-Kwang YangDepartment Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University of College of Medicine, Seoul, Korea.
Yun-Suhk SuhDepartment Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University of College of Medicine, Seoul, Korea.
Ki Bum ParkDepartment of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Sang-Hoon AhnDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Dong Woo ShinDepartment of Surgery, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
Ye Seob JeeDepartment of Surgery, Dankook University Hospital, Cheonan, Korea.
Hye-Seong AhnDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Sol LeeDepartment of Surgery, Seoul Medical Center, Seoul, Korea.
Jae Seok MinDepartment of Surgery, Dongnam Institute of Radiological and Medical Sciences, Busan, Korea.
Haejin InDepartment of Surgery, Albert Einstein College of Medicine, New York, NY, USA.
Ahyoung KimDepartment of Psychology, Ewha Womans University, Seoul, Korea.
Hoon HurDepartment of Surgery, Ajou University Hospital, Suwon, Korea.
Hyuk-Joon LeeDepartment Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University of College of Medicine, Seoul, Korea.
KOrean QUality of life in Stomach cancer patients Study group (KOQUSS)

Funding

HSRD VA HIR 10-001Korean Gastric Cancer AssociationNational Cancer Center 1910242
6 · The paper itself

Abstract

purposePatients who have undergone gastrectomy have unique symptoms that are not appropriately assessed using currently available tools. This study developed and validated a symptom-focused quality of life (QoL) questionnaire for patients who have received gastrectomy for gastric cancer. MATERIALS AND

methodsBased on a literature review, patient interviews, and expert consultation by the KOrean QUality of life in Stomach cancer patients Study group (KOQUSS), the initial item pool was developed. Two large-scale developmental studies were then sequentially conducted for exploratory factor analyses for content validity and item reduction. The final item pool was validated in a separate cohort of patients and assessed for internal consistency, test-retest reliability, construct validity, and clinical validity.

resultsThe initial questionnaire consisted of 46-items in 12 domains. Data from 465 patients at 11 institutions, followed by 499 patients at 13 institutions, were used to conduct item reduction and exploratory factor analyses. The final questionnaire (KOQUSS-40) comprised 40 items within 11 domains. Validation of KOQUSS-40 was conducted on 413 patients from 12 hospitals. KOQUSS-40 was found to have good model fit. The mean summary score of the KOQUSS-40 was correlated with the EORTC QLQ-C30 and STO22 (correlation coefficients, 0.821 and 0.778, respectively). The KOQUSS-40 score was also correlated with clinical factors, and had acceptable internal consistency (> 0.7). Test-retest reliability was greater than 0.8.

conclusionThe KOQUSS-40 can be used to assess QoL of gastric cancer patients after gastrectomy and allows for a robust comparison of surgical techniques in clinical trials.

Indexed as

Quality of LifeAgedFemaleGastrectomyHumansMaleMiddle AgedPostgastrectomy SyndromesPsychometricsReproducibility of ResultsStomach NeoplasmsSurveys and QuestionnairesQuality of lifeStomach neoplasmsSurveys and questionnairesValidation study

Identifiers

PMID33421981
PMCPMC8291178

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.