Evidence map›Paper›PMID 33421347›Full record

ReviewPharmacology research & perspectives2021

Drug-drug interactions with candidate medications used for COVID-19 treatment: An overview.

Haleh Rezaee, Fariba Pourkarim, Samira Pourtaghi-Anvarian, Taher Entezari-Maleki, Touraj Asvadi-Kermani, Masoud Nouri-Vaskeh

Open access · goldAbstract readReview
In one paragraph

Review in Pharmacology research & perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  11. Article
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  13. Molnupiravir: A new candidate for COVID-19 treatment.Pharmacology research & perspectives · 2022
    Review
  14. Review
  15. Risk of drug-induced cardiac arrhythmia during COVID-19 therapeutic treatment.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2021
    Review
  16. Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments.International journal of environmental research and public health · 2021
    Review
  17. Review
  18. Scoping insight on antiviral drugs against COVID-19.Arabian journal of chemistry · 2021
    Review
  19. Statins in COVID-19 Therapy.Life (Basel, Switzerland) · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Haleh RezaeeInfectious Diseases and Tropical Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Fariba PourkarimDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Samira Pourtaghi-AnvarianDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Taher Entezari-MalekiDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Touraj Asvadi-KermaniDepartment of Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Masoud Nouri-VaskehImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-6656-0292
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID-19; i.e., chloroquine, lopinavir/ritonavir, ribavirin, tocilizumab, and remdesivir) and increase the risk of serious adverse reactions such as QT-prolongation, retinopathy, increased risk of infection, and hepatotoxicity. This review focuses on summarizing DDIs for candidate medications used for COVID-19 in order to minimize the adverse reactions.

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2AnimalsAntibodies, Monoclonal, HumanizedAntiviral AgentsChloroquineDrug InteractionsHumansLopinavirRibavirinRitonavirAntibodies, Monoclonal, HumanizedAntiviral AgentsChloroquineLopinavirRibavirinRitonavirtocilizumabadverse reactionschloroquineCOVID-19drug-drug interactionKaletraremdesivir

Identifiers

PMID33421347
PMCPMC7796804
OpenAlexW3119796102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.