ArticleArthritis care & research2022
Comprehensive Assessment of Quality of Life, Functioning, and Mental Health in Children With Juvenile Idiopathic Arthritis and Noninfectious Uveitis.
Article in Arthritis care & research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- The impact of juvenile idiopathic arthritis on psychosocial outcomes: a systematic review and meta-analysis.Journal of pediatric psychology · 2025Pooled it
- Economic impact of Juvenile Idiopathic Arthritis: a systematic review.Pediatric rheumatology online journal · 2021Pooled it
- Mental health screening in pediatric rheumatology: a feasibility study.Pediatric rheumatology online journal · 2025Article
- Incidence, sociodemographic and presenting clinical features of childhood non-infectious uveitis: findings from the UK national inception cohort study.The British journal of ophthalmology · 2025Article
- Treatment outcomes of a Swiss non-infectious paediatric uveitis cohort: retrospective study over ten years.Journal of ophthalmic inflammation and infection · 2025Article
- Measurable Outcomes of an Ophthalmology and Rheumatology Coordinated Care Clinic.Arthritis care & research · 2025Article
- Cross-Cultural Adaptation and Validation of the Pediatric Eye Questionnaire in Chinese Children with Uveitis: A Rasch Analysis.Patient preference and adherence · 2025Article
- Comprehensive evaluation of functional vision, quality of life, and cognitive ability in pediatric uveitis.BMC ophthalmology · 2023Article
- Ophthalmic sequelae and psychosocial impact in pediatric ebola survivors.EClinicalMedicine · 2022Article
- A Blood Protein Signature Stratifies Clinical Response to csDMARD Therapy in Pediatric Uveitis.Translational vision science & technology · 2022Article
- Development of a Nationally Agreed Core Clinical Dataset for Childhood Onset Uveitis.Frontiers in pediatrics · 2022Article
- Pediatric uveitis: Role of the pediatrician.Frontiers in pediatrics · 2022Review
- Risk of anxiety and depression in patients with uveitis: a Meta-analysis.International journal of ophthalmology · 2022Article
- Next-Generation HLA Sequence Analysis Uncovers Shared Risk Alleles Between Clinically Distinct Forms of Childhood Uveitis.Investigative ophthalmology & visual science · 2021Article
Corrections and comments
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Authors and funding
22 authors at 8 institutions in 1 country.
Funding
Abstract
objectivePediatric uveitis can lead to sight-threatening complications and can impact quality of life (QoL) and functioning. We aimed to examine health-related QoL, mental health, physical disability, vision-related functioning (VRF), and vision-related QoL in children with juvenile idiopathic arthritis (JIA), JIA-associated uveitis (JIA-U), and other noninfectious uveitis. We hypothesized that there will be differences based on the presence of eye disease.
methodsA multicenter cross-sectional study was conducted at four sites. Patients with JIA, JIA-U, or noninfectious uveitis were enrolled. Patients and parents completed the Pediatric Quality of Life Inventory (PedsQL; health-related QoL), the Revised Childhood Anxiety and Depression Scale (RCADS; anxiety/depression), the Childhood Health Assessment Questionnaire (C-HAQ; physical disability), and the Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) (VRF/vision-related QoL). Clinical characteristics and patient-reported outcome measures were compared by diagnosis.
resultsOf 549 patients, 332 had JIA, 124 had JIA-U, and 93 had other uveitis diagnoses. Children with JIA-U had worse EYE-Q scores compared to those with JIA only. In children with uveitis, those with anterior uveitis (JIA-U and uveitis only) had less ocular complications, better EYE-Q scores, and worse C-HAQ and PedsQL physical summary scores compared to those with nonanterior disease. In children with anterior uveitis, those with JIA-U had worse PedsQL physical summary and C-HAQ scores than anterior uveitis only. Further, EYE-Q scores were worse in children with bilateral uveitis and more visual impairment. There were no differences in RCADS scores among groups.
conclusionWe provide a comprehensive outcome assessment of children with JIA, JIA-U, and other uveitis diagnoses. Differences in QoL and function were noted based on underlying disease. Our results support the addition of a vision-specific measure to better understand the impact of uveitis.
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