Evidence map›Paper›PMID 33420834›Full record

ArticleVirchows Archiv : an international journal of pathology2021

Desmoplastic myxoid tumor, SMARCB1-mutant: a new variant of SMARCB1-deficient tumor of the central nervous system preferentially arising in the pineal region.

Nozomi Matsumura, Naoki Goda, Konomi Yashige, Masashi Kitagawa, Tatsuya Yamazaki, Sumihito Nobusawa, Hideaki Yokoo

Abstract readCase Reports
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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Pineal Gland Parenchyma Tumors.Advances and technical standards in neurosurgery · 2026
    Review
  4. Imaging of Pineal Region Masses.Advances and technical standards in neurosurgery · 2026
    Review
  5. Article
  6. A mass in the pineal region of a young woman.Brain pathology (Zurich, Switzerland) · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nozomi MatsumuraDepartment of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan. nozomim@gunma-u.ac.jp.ORCID http://orcid.org/0000-0001-6592-6582
Naoki GodaDepartment of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Konomi YashigeDepartment of Diagnostic Pathology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Masashi KitagawaDepartment of Neurosurgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Tatsuya YamazakiDepartment of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Sumihito NobusawaDepartment of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Hideaki YokooDepartment of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desmoplastic myxoid tumor (DMT), SMARCB1-mutant is a recently proposed brain tumor that occurs in the pineal region of adults. This tumor is characterized by desmoplastic stroma and various degrees of myxoid matrix. Tumor cells with low-grade morphology show polyphenotypic immunoreactivity, and rhabdoid cells are rare. We herein present a case with some uncommon features such as no myxoid stroma and slightly elevated proliferating activity. To date, knowledge on the variety of SMARCB1/INI1-deficient tumors of the central nervous system is gradually increasing, encompassing highly aggressive to slow-growing varieties. DMT, SMARCB1-mutant seems to be relatively benign, but careful attention is necessary because SMARCB1/INI1 deficiency is generally a genetic signature of concern.

Indexed as

AdultBrain NeoplasmsChromosomal Proteins, Non-HistoneDesmoplastic Small Round Cell TumorDNA-Binding ProteinsFemaleGene ExpressionGene Expression Regulation, NeoplasticHumansPineal GlandPinealomaRhabdoid TumorSarcomaSMARCB1 ProteinTranscription FactorsTranscriptomeChromosomal Proteins, Non-HistoneDNA-Binding ProteinsSMARCB1 ProteinSMARCB1 protein, humanTranscription FactorsAtypical teratoid/rhabdoid tumorDMT, SMARCB1-mutantMyxoid stromaPineal regionSMARCB1-mutant

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.