Evidence map›Paper›PMID 33420668›Full record

ArticleClinical journal of gastroenterology2021

Early stage clear cell adenocarcinoma coexisting with tubular adenoma and adenoma with clear cell change in the colon.

Tomomasa Tochio, Youichirou Baba, Hiroki Asakawa, Kenji Nose, Satomi Tsuruga, Hiroaki Kumazawa, Yoshiaki Isono, Hiroki Tanaka, Shimpei Matsusaki, Tomohiro Sase and 4 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Clear Cell Carcinoma of the Left Colon: A Case Report.The American journal of case reports · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Tomomasa TochioDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan. toto306052@gmail.com.ORCID http://orcid.org/0000-0003-3082-3721
Youichirou BabaDepartment of Pathology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hiroki AsakawaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Kenji NoseDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Satomi TsurugaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Hiroaki KumazawaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Yoshiaki IsonoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Hiroki TanakaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Shimpei MatsusakiDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Tomohiro SaseDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Tomonori SaitoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Hiroshi OkanoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Katsumi MukaiDepartment of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka, Japan.
Ryoji KushimaDepartment of Clinical Laboratory Medicine, Shiga University of Medical Science, 520-2192, Seta Tsukinowa, Otsu, Shiga, Japan.
Shiga University of Medical Science · JPSuzuka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary clear cell adenocarcinoma (CCA) of the colorectum is rare. We report a case of a 57-year-old man with early-stage CCA with conventional tubular adenoma and tubular adenoma with clear cell change in the transverse colon, diagnosed with image-enhanced endoscopy. The tumor was then treated with endoscopic submucosal dissection. The endoscopic findings characteristic of clear cell adenoma/adenocarcinoma could not be identified. Therefore, similar diagnostic tools as for conventional colorectal adenoma/cancer were considered. The pathogenesis of the clear cell change was unknown, but it might appear with the progression of the malignancy.

Indexed as

Adenocarcinoma, Clear CellAdenomaEndoscopic Mucosal ResectionColonHumansMaleMiddle AgedAdenoma with clear cell changeClear cell adenocarcinomaColon cancerImage-enhanced endoscopyMagnifying endoscopy

Identifiers

PMID33420668
OpenAlexW3120580616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.