Evidence map›Paper›PMID 33420590›Full record

ReviewStem cell reviews and reports2021

Neglected No More: Emerging Cellular Therapies in Traumatic Injury.

Lacy E Lowry, Maryanne C Herzig, Barbara A Christy, Richard Schäfer, Shibani Pati, Andrew P Cap, James A Bynum

Open access · bronzeAbstract readReview
In one paragraph

Review in Stem cell reviews and reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Recent Advances in the Treatment of Spinal Cord Injury.The archives of bone and joint surgery · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Lacy E LowryDepartment of Internal Medicine, Brooke Army Medical Center, JBSA Fort Sam Houston, TX, USA.
Maryanne C HerzigBlood & Coagulation Research Department, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA.
Barbara A ChristyBlood & Coagulation Research Department, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA. barbara.christy3.ctr@mail.mil.ORCID http://orcid.org/0000-0001-5318-653X
Richard SchäferInstitute for Transfusion Medicine and Immunohaematology, German Red Cross Blood Donor Service Baden-Württemberg-Hessen, Goethe University Hospital, Frankfurt am Main, Germany.
Shibani PatiDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.
Andrew P CapBlood & Coagulation Research Department, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA.
James A BynumBlood & Coagulation Research Department, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX, USA.
The University of Texas Health Science Center at San Antonio · USBaylor University · USBrooke Army Medical Center · USGoethe University Frankfurt · DEUnited States Army Institute of Surgical Research · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic injuries are a leading cause of death and disability in both military and civilian populations. Given the complexity and diversity of traumatic injuries, novel and individualized treatment strategies are required to optimize outcomes. Cellular therapies have potential benefit for the treatment of acute or chronic injuries, and various cell-based pharmaceuticals are currently being tested in preclinical studies or in clinical trials. Cellular therapeutics may have the ability to complement existing therapies, especially in restoring organ function lost due to tissue disruption, prolonged hypoxia or inflammatory damage. In this article we highlight the current status and discuss future directions of cellular therapies for the treatment of traumatic injury. Both published research and ongoing clinical trials are discussed here.

Indexed as

Cell- and Tissue-Based TherapyHumansWounds and InjuriesCell therapyTrauma

Identifiers

PMID33420590
PMCPMC7793620
OpenAlexW3119126294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.