Evidence map›Paper›PMID 33420588›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2021

Serotonergic Facilitation of Forelimb Functional Recovery in Rats with Cervical Spinal Cord Injury.

Benita Jin, Monzurul Alam, Alexa Tierno, Hui Zhong, Roland R Roy, Yury Gerasimenko, Daniel C Lu, V Reggie Edgerton

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of chemogenetic virus injection and clozapine administration in spinal cord injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Benita Jin *Department of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Monzurul Alam *Department of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Alexa TiernoDepartment of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Hui ZhongDepartment of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Roland R RoyDepartment of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Yury GerasimenkoDepartment of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA.
Daniel C LuDepartment of Neurosurgery, University of California, Los Angeles, CA, 90095, USA.
V Reggie EdgertonDepartment of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive, Los Angeles, CA, 90095-1527, USA. vre@ucla.edu.ORCID http://orcid.org/0000-0001-6534-1875
University of California, Los Angeles · USUniversity of Technology Sydney · AU

Funding

Enabling forelimb function with agonist drug and epidural stimulation in SCIU01EB015521 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EDGERTON, REGGIE, LU, DANIEL · 2013 to 2017
$6.0M
Transformation of Paraplegic Paralysis to Overground Stepping in HumansR01NS102920 · NINDS · UNIVERSITY OF LOUISVILLE · PI OVECHKIN, ALEXANDER VLADIMIROVICH · 2019 to 2023
$2.8M
NIBIB NIH HHS U01 EB015521NINDS NIH HHS R01 NS102920
6 · The paper itself

Abstract

Serotonergic agents can improve the recovery of motor ability after a spinal cord injury. Herein, we compare the effects of buspirone, a 5-HT

Indexed as

AnimalsBuspironeCervical CordElectromyographyEvoked Potentials, MotorFemaleFluoxetineForelimbHand StrengthRatsRats, Long-EvansRecovery of FunctionSelective Serotonin Reuptake InhibitorsSerotonin Receptor AgonistsSpinal Cord InjuriesBuspironeFluoxetineSelective Serotonin Reuptake InhibitorsSerotonin Receptor AgonistsBuspironeFluoxetineForelimbSerotoninSpinal cord injury

Identifiers

PMID33420588
PMCPMC8423890
OpenAlexW3120042889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.