Evidence map›Paper›PMID 33420583›Full record

Trial reportChinese journal of integrative medicine2021

Effect of Tai Chi and Resistance Training on Cancer-Related Fatigue and Quality of Life in Middle-Aged and Elderly Cancer Patients.

Duan Cheng, Xuan Wang, Jie Hu, Ling-Li Dai, Ying Lv, Hui Feng, Yan Zhang, Yan Guo, Lei Wang

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Chinese journal of integrative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 14 pooled it
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 14 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  6. Resistance training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2024
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  7. Effects of resistance training on quality of life, fatigue, physical function, and muscular strength during chemotherapy treatment: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  11. Efficacy of resistance training during adjuvant chemotherapy and radiation therapy in cancer care: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  15. Trial
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  17. Gut Microbiota-Driven Pathways Linking Chronic Stress to Tumor Progression.International journal of biological sciences · 2026
    Review
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  20. The association between physical activity levels and quality of life in elderly lung cancer patients undergoing chemotherapy in China: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Duan ChengDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Xuan WangDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jie HuDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ling-Li DaiDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ying LvDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Hui FengDepartment of Rehabiliation Medicine, Nanjing Jiangning Hospital, Nanjing, 211101, China.
Yan ZhangDepartment of Oncology, Jiangsu Cancer Hospital, Nanjing, 210009, China.
Yan GuoXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. guoyan0314@126.com.
Lei WangDepartment of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. pitx3@163.com.
Nanjing University of Chinese Medicine · CNJiangsu Cancer Hospital · CNNanjing Jiangning Hospital · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of Tai Chi (TC) and resistance training (RT) with different intensity on the cancer-related fatigue (CRF) and quality of life (QoL) of middle-aged and elderly cancer patients.

methodsTotally 120 cancer patients were enrolled and randomly assigned to 4 groups by a random number table, including TC group, high-intensity 60% one repetition maximum (1-RM) RT group (HIRT), low-intensity (30% 1-RM) RT group (LIRT) and control group, 30 patients in each group. Participants in the TC group received 24-form simplified Yang-style TC training at a frequency of 40 min per day, 3 days per week for 12 weeks. Patients in the two RT groups received 10 sessions, 6 designated movements per day, 3 days per week for 12 weeks. The 1-RM of 6 muscle groups, fat mass (FM), lean body mass (LBM), along with the scores of Brief Fatigue Inventory (BFI), QoL questionnaire for Chinese cancer patients receiving chemobiotherapy (QLQ-CCC), Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9) and Pittsburgh Sleep Quality Index (PSQI) were measured before and after training. The adverse effect was also observed.

resultsAfter 12-week intervention, patients in both TC and RT groups showed significant improvements in CRF and QLQ-CCC compared to pre-treatment (P<0.05). Compared with the LIRT and TC groups, patients in the HIRT group improved more significantly in increasing muscle strength and LBM, and reducing in FM (P<0.05). Patients in the TC group significantly increased in lower limb muscle strength compared with the LIRT group (P<0.05). In addition, patients in the TC group showed more significant improvements in scores of GAD-7, PHQ-9 and PSQI than 2 RT groups (P<0.05).

conclusionsTC and RT, both low- and high-intensity training, can significantly increase muscle strength, reduce CRF and improve QoL in the middle-aged and elderly cancer patients. TC has a better effect than RT in terms of sleep quality and mental health. The long-term application is needed to substantiate the effect of TC as an alternative exercise in cancer patients.

Indexed as

FatigueNeoplasmsResistance TrainingTai JiAgedHumansMiddle AgedQuality of Lifecancer-related fatiguequality of liferesistance trainingTai chi

Identifiers

PMID33420583
OpenAlexW3119241462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.