ArticleInternational ophthalmology2021
Evaluation of retinal vessel density and foveal avascular zone measurements in patients with obstructive sleep apnea syndrome.
Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Microvascular changes in the macular area in patients with obstructive sleep apnoea syndrome compared to controls: A systematic review and meta-analysis.Eye (London, England) · 2026Pooled it
- Evaluation of retinal microcirculation in hypertensive patients with obstructive sleep apnea: a subgroup analysis based on asymptomatic organ damage.International ophthalmology · 2026Article
- Selected Retinal and Choroidal Parameters Assessed by Optical Coherence Tomography and Optical Coherence Tomography Angiography in Patients With Obstructive Sleep Apnea.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Alterations in the DTI-ALPS index and choroid plexus volume are associated with symptom severity in children with tic disorders.BMC neurology · 2026Article
- Choroidal vascular and oropharyngeal morphological indicators in predicting CPAP treatment efficacy in severe OSAS patients: a prospective cohort study.Head & face medicine · 2025Article
- Evaluation of retinal vascular structure via optic coherence tomography angiography in obstructive sleep apnea.International ophthalmology · 2025Article
- Tonsillectomy and/or adenoidectomy improves macular microcirculation in children with obstructive sleep apnea.Scientific reports · 2025Article
- Retinal microvascular density and inner thickness in Alzheimer's disease and mild cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Analysis of Macular Vascularization Using Optical Coherence Tomography Angiography in Patients with Obstructive Sleep Apnea Syndrome: A Prospective Clinical Study.Medicina (Kaunas, Lithuania) · 2024Article
- Meta-Analysis: Characteristics of Retinal Vasculature in Obstructive Sleep Apnea Syndrome Humans.Journal of ophthalmology · 2024Article
- Effects of obstructive sleep apnea on retinal microvasculature.International journal of ophthalmology · 2023Article
- Decreased Peripapillary and Macular Vascular Densities in Patients with Moderate/Severe Obstructive Sleep Apnea/Hypopnea Syndrome.Nature and science of sleep · 2023Article
- Retinal microcirculation characteristics in obstructive sleep apnea/hypopnea syndrome evaluated by OCT-angiography: a literature review.International ophthalmology · 2022Review
- Choroidal vascularity index in obstructive sleep apnea syndrome.Sleep & breathing = Schlaf & Atmung · 2022Article
- A lightweight deep learning model for automatic segmentation and analysis of ophthalmic images.Scientific reports · 2022Article
- Examining the Relationship Between Diabetic Macular Edema, and Obstructive Sleep Apnea.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Association of self-reported snoring with decreased retinal thickness and vessel density.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare retinal capillary plexus vessel densities, choroidal thickness, optic disc vessel densities and foveal avascular zone measurements between normal subjects and subjects with obstructive sleep apnea syndrome (OSAS) using spectral-domain OCT angiography (OCTA).
methodsForty eyes of patients with overall OSAS, 20 eyes of patients with mild-moderate OSAS, 20 eyes of patients with severe OSAS on polysomnography and 21 controls were evaluated with the RTVue-XR Avanti OCTA (Optovue, Inc., Fremont, CA). Superficial and deep retinal capillary plexus vessel densities, choroidal thickness and foveal avascular zone (FAZ) parameters (area, diameter, acircularity index of the FAZ, foveal density-300) were measured for all subjects.
resultsSuperficial capillary plexus vessel densities of the groups were similar. Deep capillary plexus (DCP) vessel densities of all three OSAS groups decreased in the parafoveal region (< 0.001). In the perifoveal region, DCP vessel densities were decreased in the Overall OSAS group (p = 0.023) and in the Severe OSAS group (p = 0.021), whereas it was similar in the Mild-moderate OSAS group. Choroidal thickness decreased in all three OSAS groups (p < 0.001). All FAZ measurements and foveal density-300 measurements were similar compared to the control group.
conclusionOur findings indicate that in severe OSAS patients, deep parafoveal, perifoveal vascular densities decrease and the choroid layer becomes thinner. When evaluating a patient with OSAS, it should be kept in mind that there may be eye involvement due to the disease.
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