ArticleJournal of urban health : bulletin of the New York Academy of Medicine2021
Neighborhood Characteristics and Cardiovascular Biomarkers in Middle-Aged and Older Adults: the Baltimore Memory Study.
Article in Journal of urban health : bulletin of the New York Academy of Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Association of long-term exposure to green space with cardiovascular health and the mediating role of triglyceride-glucose in dex in middle-aged and older Chinese adults: a nationwide cohort study.Journal of geriatric cardiology : JGC · 2026Article
- Uncovering the biological toll of neighborhood disorder trajectories: a machine learning based weighting analysis of biomarkers in older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Multilevel Mediators on the Associations of Neighborhood Social Environmental Factors and Severity of Metabolic Syndrome: The Jackson Heart Study.Journal of the American Heart Association · 2025Article
- Uncovering the Biological Toll of Neighborhood Physical Disorder: Links to Metabolic and Inflammatory Biomarkers in Older Adults.medRxiv : the preprint server for health sciences · 2024Article
- Associations between neighborhood socioeconomic deprivation, IFNγ, and high-density lipoprotein particle size: Data from the Washington, D.C. cardiovascular health and needs assessment.Psychoneuroendocrinology · 2023Observational
- Neighborhood Social Determinants of Health in Patients Seen in Neurology Movement Disorders Clinics.Neurology. Clinical practice · 2023Article
- Greenspace and mortality in the U.K. Biobank: Longitudinal cohort analysis of socio-economic, environmental, and biomarker pathways.SSM - population health · 2022Article
- Mothers with justice-involved sons: Socioeconomic impacts of COVID-19 by neighborhood disorder in the United States.The Journal of social issues · 2022Article
- Childhood Neighborhood Disadvantage, Parenting, and Adult Health.American journal of preventive medicine · 2022Article
- Residential Street Block Disorder and Biological Markers of Aging in Older Adults: The National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Neighborhood greenness has been linked to better cardiovascular health, but little is known about its association with biomarkers related to cardiovascular risk. Adverse neighborhood conditions, such as disorder and socioeconomic disadvantage, are associated with higher cardiovascular biomarker levels, but these relationships may differ in neighborhoods with more greenness. This study evaluated cross-sectional associations of validated measures of neighborhood greenness, disorder, and socioeconomic disadvantage with cardiovascular biomarkers in middle-aged and older adults living in Baltimore City. The sample included 500 adults, aged 57-79 years, enrolled in the Baltimore Memory Study and living in Baltimore City during 2009-2010. Multi-level log-gamma regressions examined associations between the three neighborhood characteristics and seven cardiovascular biomarkers. Models additionally evaluated the effect modification by neighborhood greenness on associations of neighborhood disorder and socioeconomic disadvantage with the biomarkers. Adjusting for covariates and neighborhood greenness, greater neighborhood disorder was associated with higher C-reactive protein (exp β = 1.21, SE = 0.11, p = 0.035) and serum amyloid A (exp β = 1.28, SE = 0.12, p = 0.008), while greater neighborhood socioeconomic disadvantage was associated with higher tumor necrosis factor alpha (exp β = 1.24, SE = 0.12, p = 0.019). Higher neighborhood greenness was associated with lower soluble vascular cell adhesion molecule-1, accounting for disorder (exp β = 0.70, SE = 0.10, p = 0.010) and socioeconomic disadvantage (exp β = 0.73, SE = 0.10, p = 0.025). There was no evidence of effect modification among neighborhood characteristics. The findings suggest that neighborhood effects on cardiovascular health may be mediated through cardiovascular biomarker levels, and that socioeconomic disadvantage, disorder, and greenness may each be important features of neighborhoods.
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