Evidence map›Paper›PMID 33420277›Full record

Trial reportScientific reports2021

Effects of different vibration frequencies on muscle strength, bone turnover and walking endurance in chronic stroke.

Zhenhui Yang, Tiev Miller, Zou Xiang, Marco Y C Pang

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Exploring the Impact of Muscle Vibration Therapy in Neurologic Rehabilitation: A Systematic Review.Archives of rehabilitation research and clinical translation · 2025
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Zhenhui YangDepartment of Rehabilitation Sciences, Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Hong Kong.
Tiev MillerDepartment of Rehabilitation Sciences, Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Hong Kong.
Zou XiangDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Marco Y C PangDepartment of Rehabilitation Sciences, Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Hong Kong. marco.pang@polyu.edu.hk.
Hong Kong Polytechnic University · HKGuangdong Work Injury Rehabilitation Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This randomized controlled trial aimed to evaluate the effects of different whole body vibration (WBV) frequencies on concentric and eccentric leg muscle strength, bone turnover and walking endurance after stroke. The study involved eighty-four individuals with chronic stroke (mean age = 59.7 years, SD = 6.5) with mild to moderate motor impairment (Fugl-Meyer Assessment lower limb motor score: mean = 24.0, SD = 3.5) randomly assigned to either a 20 Hz or 30 Hz WBV intervention program. Both programs involved 3 training sessions per week for 8 weeks. Isokinetic knee concentric and eccentric extension strength, serum level of cross-linked N-telopeptides of type I collagen (NTx), and walking endurance (6-min walk test; 6MWT) were assessed at baseline and post-intervention. An intention-to-treat analysis revealed a significant time effect for all muscle strength outcomes and NTx, but not for 6MWT. The time-by-group interaction was only significant for the paretic eccentric knee extensor work, with a medium effect size (0.44; 95% CI: 0.01, 0.87). Both WBV protocols were effective in improving leg muscle strength and reducing bone resorption. Comparatively greater improvement in paretic eccentric leg strength was observed for the 30 Hz protocol.

Indexed as

VibrationAgedBone RemodelingFemaleHumansLegMaleMiddle AgedMuscle, SkeletalMuscle StrengthStrokeStroke RehabilitationWalking

Identifiers

PMID33420277
PMCPMC7794423
OpenAlexW3120017398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.