Evidence map›Paper›PMID 33420263›Full record

ArticleScientific reports2021

Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis.

Yoshiyuki Akiyama, Masayoshi Zaitsu, Daiji Watanabe, Itsuki Yoshimura, Aya Niimi, Akira Nomiya, Yuta Yamada, Yusuke Sato, Masaki Nakamura, Taketo Kawai and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Yoshiyuki AkiyamaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan. yakiyamauro-tky@umin.ac.jp.ORCID 0000-0003-1439-5640
Masayoshi ZaitsuDepartment of Public Health, Dokkyo Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0001-7616-355X
Daiji WatanabeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0001-6651-589X
Itsuki YoshimuraDepratment of Urology, Teikyo University School of Medicine, Tokyo, Japan.ORCID 0000-0001-5689-2384
Aya NiimiDepartment of Urology, New Tokyo Hospital, MatsudoTokyo, Chiba, Japan.ORCID 0000-0002-4828-7851
Akira NomiyaDepartment of Urology, National Center for Global Health and Medicine, Tokyo, Japan.ORCID 0000-0001-6698-8232
Yuta YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0002-9698-4301
Yusuke SatoDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0002-6239-6050
Masaki NakamuraDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0002-7473-3325
Taketo KawaiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0002-7279-2874
Daisuke YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0002-2296-6653
Motofumi SuzukiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0003-2552-1964
Haruki KumeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, Japan.ORCID 0000-0001-9841-0857
Yukio HommaJapanese Red Cross Medical Center, Tokyo, Japan.ORCID 0000-0002-4794-5250
The University of Tokyo · JPDokkyo Medical University · JPJapanese Red Cross Medical Center · JPNational Center for Global Health and Medicine · JPNew Tokyo Hospital · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrocautery is a promising treatment option for patients with Hunner type interstitial cystitis (HIC), but frequently requires multiple sessions due to recurrence of the lesions. In the present study, we assessed the relationship between the frequency of electrocautery of Hunner lesions and changes in maximum bladder capacity (MBC) at hydrodistension in a large cohort of 118 HIC patients. Three mixed-effect linear regression analyses were conducted for MBC against (1) the number of sessions; (2) the number of sessions and the time between each session and the first session; and (3) other relevant clinical parameters in addition to the Model (2). The mean number of sessions was 2.8 times. MBC decreased approximately 50 mL for each additional electrocautery session, but this loss was offset by 10 mL for each year the subsequent session was postponed. MBC of < 400 mL at the first session was a significant risk factor for MBC loss with further sessions. No other clinical parameters were associated with MBC over time. This study demonstrates a significant relationship between the frequency of electrocautery of Hunner lesions and MBC changes in HIC patients. Low MBC at the first session is a poor prognostic marker for MBC loss over multiple sessions.

Indexed as

ElectrocoagulationAdultAgedAged, 80 and overCohort StudiesCystitis, InterstitialFemaleHumansMaleMiddle AgedTreatment OutcomeUrinary BladderUrination

Identifiers

PMID33420263
PMCPMC7794499
OpenAlexW3121036519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.