Evidence map›Paper›PMID 33420205›Full record

ArticleScientific reports2021

Automated segmentation of endometrial cancer on MR images using deep learning.

Erlend Hodneland, Julie A Dybvik, Kari S Wagner-Larsen, Veronika Šoltészová, Antonella Z Munthe-Kaas, Kristine E Fasmer, Camilla Krakstad, Arvid Lundervold, Alexander S Lundervold, Øyvind Salvesen and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Artificial Intelligence in Obstetric and Gynecological MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Erlend HodnelandNORCE Norwegian Research Centre, Bergen, Norway. erlend.hodneland@uib.no.
Julie A DybvikDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Kari S Wagner-LarsenDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Veronika ŠoltészováNORCE Norwegian Research Centre, Bergen, Norway.
Antonella Z Munthe-KaasDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Kristine E FasmerDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Camilla KrakstadDepartment of Clinical Science, Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway.
Arvid LundervoldDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Alexander S LundervoldDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.
Øyvind SalvesenDepartment of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
Bradley J EricksonDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ingfrid HaldorsenDepartment of Radiology, MMIV Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway.

Funding

Trond Mohn Foundation BFS2018TMT06
6 · The paper itself

Abstract

Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses of MR images may provide radiomic tumor signatures potentially relevant for better individualization and optimization of treatment. We apply a convolutional neural network for automatic tumor segmentation in endometrial cancer patients, enabling automated extraction of tumor texture parameters and tumor volume. The network was trained, validated and tested on a cohort of 139 endometrial cancer patients based on preoperative pelvic imaging. The algorithm was able to retrieve tumor volumes comparable to human expert level (likelihood-ratio test, [Formula: see text]). The network was also able to provide a set of segmentation masks with human agreement not different from inter-rater agreement of human experts (Wilcoxon signed rank test, [Formula: see text], [Formula: see text], and [Formula: see text]). An automatic tool for tumor segmentation in endometrial cancer patients enables automated extraction of tumor volume and whole-volume tumor texture features. This approach represents a promising method for automatic radiomic tumor profiling with potential relevance for better prognostication and individualization of therapeutic strategy in endometrial cancer.

Indexed as

Deep LearningMagnetic Resonance ImagingAutomationEndometrial NeoplasmsFemaleHumansImage Processing, Computer-AssistedTumor Burden

Identifiers

PMID33420205
PMCPMC7794479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.