ArticleScientific reports2021
Diagnostic accuracy of tomosynthesis-guided vacuum assisted breast biopsy of ultrasound occult lesions.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Histopathological Analysis of Vacuum-Assisted Breast Biopsy in Relation to Microcalcification Findings on Mammography: A Pictorial Review.Biomedicines · 2025Review
- Comparison of two visual localization biopsy methods for suspicious breast lesions under mammography: a multicenter cohort study.Quantitative imaging in medicine and surgery · 2025Article
- Tomosynthesis-Guided Biopsy: A Troubleshooting Guide.Diagnostics (Basel, Switzerland) · 2025Review
- Role of Image-Guided Biopsy in Nonpalpable Breast Lesions: A Study in the Sub-Himalayan Region of North India.South Asian journal of cancer · 2025Article
- A machine learning-based predictive model for complication risks in vacuum-assisted breast biopsy.Frontiers in surgery · 2025Article
- Tips and Tricks for Image-Guided Breast Biopsies: Technical Factors for Success.Journal of breast imaging · 2024Review
- Practical Challenges of DBT-Guided VABB: Harms and Benefits, from Literature to Clinical Experience.Cancers · 2023Article
- Digital tomosynthesis spot view in architectural distortions: outcomes in management and radiation dose.La Radiologia medica · 2023Article
- Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit.SA journal of radiology · 2022Article
- Architectural distortion outcome: digital breast tomosynthesis-detected versus digital mammography-detected.La Radiologia medica · 2022Article
- Regulatory mechanisms and potential medical applications of HNF1A-AS1 in cancers.American journal of translational research · 2022Review
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Authors and funding
7 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
This study aims to evaluate the diagnostic accuracy of digital breast tomosynthesis-guided vacuum assisted breast biopsy (DBT-VABB) of screening detected suspicious mammographic abnormalities comprising of calcifications, asymmetric densities, architectural distortions and spiculated masses. In this institutionally approved study, a total of 170 (n = 170) DBT-VABB were performed, 153 (90%) were for calcifications, 8 (4.7%) for spiculated mass, 5 (2.9%) for asymmetric density and 4 (2.4%) for architectural distortion. All these lesions were not detected on the corresponding ultrasound. Histopathology results revealed 140 (82.4%) benign, 9 (5.3%) borderline and 21 (12.4%) malignant lesions. The total upgrade rate at surgery was 40% for atypical ductal hyperplasia and 5.9% for ductal carcinoma in-situ. 3.6% discordant benign lesions showed no upgrade. DBT-VABB showed 100% specificity, 91.3% sensitivity and 100% positive predictive value (PPV) for detecting malignant lesions. The negative predictive value (NPV) was 80%. 2 (1.2%) patients had mild complications and 1 (0.6%) had severe pain. Our study showed that DBT-VABB was a safe and reliable method, with high sensitivity, specificity, PPV and NPV in the diagnosis of non-palpable benign and malignant breast lesions. Our data also confirmed the accuracy of DBT-VABB in detecting malignant lesions and we suggest further surgical excision in borderline lesions for a more accurate diagnostic evaluation.
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