Evidence map›Paper›PMID 33419945›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Evaluation of Safety and Dosimetry of

René Fernández, Elisabeth Eppard, Wencke Lehnert, Luis David Jiménez-Franco, Cristian Soza-Ried, Matías Ceballos, Jessica Ribbeck, Andreas Kluge, Frank Rösch, Marian Meckel and 3 more

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. First-in-human study of dosimetry, safety and efficacy for [European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. Biodistribution and dosimetry ofEJNMMI research · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. A review of advances in the last decade on targeted cancer therapy usingAmerican journal of nuclear medicine and molecular imaging · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

René FernándezCenter for Nuclear Medicine and PET/CT, PositronMed, Santiago, Chile.
Elisabeth EppardPositronpharma SA, Santiago, Chile; eeppard@positronpharma.cl.
Wencke LehnertABX-CRO, Dresden, Germany.
Luis David Jiménez-FrancoABX-CRO, Dresden, Germany.
Cristian Soza-RiedCenter for Nuclear Medicine and PET/CT, PositronMed, Santiago, Chile.
Matías CeballosCenter for Nuclear Medicine and PET/CT, PositronMed, Santiago, Chile.
Jessica RibbeckPositronpharma SA, Santiago, Chile.
Andreas KlugeABX-CRO, Dresden, Germany.
Frank RöschInstitute of Nuclear Chemistry, Johannes Gutenberg-University, Mainz, Germany; and.
Marian MeckelIsotope Technologies Garching GmbH, Munich, Germany.
Konstantin ZhernosekovIsotope Technologies Garching GmbH, Munich, Germany.
Vasko KramerCenter for Nuclear Medicine and PET/CT, PositronMed, Santiago, Chile.
Horacio AmaralCenter for Nuclear Medicine and PET/CT, PositronMed, Santiago, Chile.
Positron (United States) · USABX-CRO Advanced Pharmaceutical Services (Germany) · DEIsotopen Technologien München (Germany) · DEJohannes Gutenberg University Mainz · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palliative treatment of bone metastasis using radiolabeled bisphosphonates is a well-known concept proven to be safe and effective. A new therapeutic radiopharmaceutical for bone metastasis is

Indexed as

Bone NeoplasmsRadiometrySingle Photon Emission Computed Tomography Computed TomographyAgedAged, 80 and overDiphosphonatesHumansImidazolesLutetiumMaleMiddle AgedOrganometallic CompoundsProstatic Neoplasms, Castration-ResistantRadioisotopesRadiopharmaceuticalsSafetyDiphosphonatesImidazolesLutetiumOrganometallic CompoundsRadioisotopesRadiopharmaceuticals177Lu-DOTA-ZOLbisphosphonatebone metastasisdosimetryradionuclide therapy

Identifiers

PMID33419945
PMCPMC8833870
OpenAlexW3121013252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.