Evidence map›Paper›PMID 33419777›Full record

ArticleJournal of cell science2021

Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast.

Elizabeth Scotchman, Kazunori Kume, Francisco J Navarro, Paul Nurse

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evolutionary Advantage of Cell Size Control.Physical review letters · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Elizabeth ScotchmanCell Cycle Laboratory, The Francis Crick Institute, London NW1 1AT, UK.ORCID 0000-0001-7418-6037
Kazunori KumeCell Cycle Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Francisco J NavarroCell Cycle Laboratory, The Francis Crick Institute, London NW1 1AT, UK fnavarro@cantab.net paul.nurse@crick.ac.uk.ORCID 0000-0002-9332-0737
Paul NurseCell Cycle Laboratory, The Francis Crick Institute, London NW1 1AT, UK fnavarro@cantab.net paul.nurse@crick.ac.uk.ORCID 0000-0002-9244-7787
The Francis Crick Institute · GBHiroshima University · JP

Funding

Cancer Research UK FC01121Medical Research Council FC01121Wellcome Trust 214183Wellcome Trust FC001121Wellcome Trust FC01121
6 · The paper itself

Abstract

Fission yeast cells divide at a similar cell length with little variation about the mean. This is thought to be the result of a control mechanism that senses size and corrects for any deviations by advancing or delaying onset of mitosis. Gene deletions that advance cells into mitosis at a smaller size or delay cells entering mitosis have led to the identification of genes potentially involved in this mechanism. However, the molecular basis of this control is still not understood. In this work, we have screened for genes that when deleted increase the variability in size of dividing cells. The strongest candidate identified in this screen was

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsCell CycleCell SizeMitosisSchizosaccharomyces pombe ProteinsFission yeastmga2MitosisSize control

Identifiers

PMID33419777
PMCPMC7888708
OpenAlexW3118256323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.