Evidence map›Paper›PMID 33419482›Full record

ArticleAdvances in rheumatology (London, England)2021

Increased modifiable cardiovascular risk factors in patients with Takayasu arteritis: a multicenter cross-sectional study.

Alexandre Moura Dos Santos, Rafael Giovani Misse, Isabela Bruna Pires Borges, Bruno Gualano, Alexandre Wagner Silva de Souza, Liliam Takayama, Rosa Maria R Pereira, Samuel Katsuyuki Shinjo

Registry-linked trialOpen access · diamondAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Advances in rheumatology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06807788 (Evaluation of Platelet Aggregability in Patients with Takayasu's Arteritis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06807788 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Platelet Aggregability in Patients with Takayasu's Arteritis

TypeobservationalSponsorJose Carlos NicolauRan2024 to 2027Enrolled100ConditionsTakayasu Arteritis (TAK), Vasculitis, SystemicArmsClopidogrel
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alexandre Moura Dos SantosDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Rafael Giovani MisseDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Isabela Bruna Pires BorgesDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Bruno GualanoDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Alexandre Wagner Silva de SouzaDivision of Rheumatology, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil.
Liliam TakayamaDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Rosa Maria R PereiraDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Samuel Katsuyuki ShinjoDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil. samuel.shinjo@usp.br.ORCID 0000-0002-3682-4517
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundModifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Therefore, the aim of the study was to investigate MCRFs and their relationships with disease status and comorbidities among patients with TAK.

methodsA multicenter cross-sectional study was conducted between 2019 and 2020, in which 20 adult women with TAK were compared with 16 healthy controls matched by gender, age, and body mass index. The following parameters were analyzed: aerobic capacity by cardiopulmonary test; muscle function by timed-stands test, timed up-and-go test, and handgrip test; muscle strength by one-repetition maximum test and handgrip test; body composition by densitometry; physical activity and metabolic equivalent by IPAQ, quality of life by HAQ and SF-36; disease activity by ITAS2010 and NIH score; and presence of comorbidities.

resultsPatients with TAK had a mean age of 41.5 (38.0-46.3) years, disease duration of 16.0 (9.5-20.0) years, and a mean BMI of 27.7±4.5 kg/m

conclusionsTAK show impairment in MCRFs; therefore, strategies able to improve MCRF should be considered in this disease.

Indexed as

Heart Disease Risk FactorsAdultAge FactorsBody Mass IndexCardiorespiratory FitnessCase-Control StudiesComorbidityCross-Sectional StudiesDiabetes Mellitus, Type 2DyslipidemiasFemaleHand StrengthHumansHypertensionMaleMiddle AgedAerobic capacityCardiovascular diseasesMuscle strengthVasculitis

Identifiers

PMID33419482
OpenAlexW3119653212

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.