Evidence map›Paper›PMID 33419471›Full record

ArticleBiotechnology for biofuels2021

Process optimization for mass production of 2,3-butanediol by Bacillus subtilis CS13.

Dexin Wang, Baek-Rock Oh, Sungbeom Lee, Dae-Hyuk Kim, Min-Ho Joe

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mutagenesis and Analysis for Enhancing (2Molecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Production of Tetramethylpyrazine from Cane Molasses byMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dexin WangRadiation Utilization and Facilities Management Division, Korea Atomic Energy Research Institute, 29 Geumgu-gil, Jeongeup, 56212, Republic of Korea.
Baek-Rock OhMicrobial Biotechnology Research Center, Jeonbuk Branch Institute, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, 56212, Republic of Korea.
Sungbeom LeeRadiation Research Division, Korea Atomic Energy Research Institute, 29 Geumgu-gil, Jeongeup, 56212, Republic of Korea.
Dae-Hyuk KimDepartment of Bioactive Material Sciences, Institute for Molecular Biology and Genetics, Center for Fungal Pathogenesis, Jeonbuk National University, Jeonju, 54896, Republic of Korea.
Min-Ho JoeRadiation Utilization and Facilities Management Division, Korea Atomic Energy Research Institute, 29 Geumgu-gil, Jeongeup, 56212, Republic of Korea. jomino@kaeri.re.kr.ORCID http://orcid.org/0000-0001-8786-057X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacillus subtilis CS13 was previously isolated for 2,3-butanediol (2,3-BD) and poly-γ-glutamic acid (γ-PGA) co-production. When culturing this strain without L-glutamic acid in the medium, 2,3-BD is the main metabolic product. 2,3-BD is an important substance and fuel with applications in the chemical, food, and pharmaceutical industries. However, the yield and productivity for the B. subtilis strain should be improved for more efficient production of 2,3-BD.

resultsThe medium composition, which contained 281.1 g/L sucrose, 21.9 g/L ammonium citrate, and 3.6 g/L MgSO

conclusionsThe production of 2,3-BD by B. subtilis CS13 showed a higher concentration, productivity, and yield compared to the reported generally recognized as safe 2,3-BD producers. These results suggest that B. subtilis CS13 is a promising strain for industrial-scale production of 2,3-BD.

Indexed as

2,3-butanediolB. subtilis CS13FermentationResponse surface methodology

Identifiers

PMID33419471
PMCPMC7791975

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.